Literature DB >> 3660592

Identification of endogenous retroviral sequences as potential donors for recombinational repair of mutant retroviruses: positions of crossover points.

J Colicelli1, S P Goff.   

Abstract

Mutants of Moloney murine leukemia virus carrying deletions in essential regions of the genome can revert after infection of mouse cells by recombination with endogenous retroviral sequences. We have identified cloned DNAs containing potential donor sequences for two such recombination events and determined the nucleotide sequences in the relevant regions. Comparison of these sequences with that of the original mutants and the revertant viruses allowed a determination of the crossover points that were used in formation of the revertants. Each crossover occurred in short stretches (17-24 bp) of perfect homology between the two parent sequences.

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Year:  1987        PMID： 3660592     DOI： 10.1016/0042-6822(87)90030-4

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  7 in total

1.  Recombination in the 5' leader of murine leukemia virus is accurate and influenced by sequence identity with a strong bias toward the kissing-loop dimerization region.

Authors:  J G Mikkelsen; A H Lund; M Duch; F S Pedersen
Journal:  J Virol       Date:  1998-09       Impact factor: 5.103

2.  Extended minus-strand DNA as template for R-U5-mediated second-strand transfer in recombinational rescue of primer binding site-modified retroviral vectors.

Authors:  J G Mikkelsen; A H Lund; K Dybkaer; M Duch; F S Pedersen
Journal:  J Virol       Date:  1998-03       Impact factor: 5.103

3.  Mutations of the kissing-loop dimerization sequence influence the site specificity of murine leukemia virus recombination in vivo.

Authors:  J G Mikkelsen; A H Lund; M Duch; F S Pedersen
Journal:  J Virol       Date:  2000-01       Impact factor: 5.103

4.  Transduction of proto-src sequences in tissue culture by a molecular clone of transformation-defective Rous sarcoma virus with an internal src deletion.

Authors:  W Phares
Journal:  J Virol       Date:  1988-12       Impact factor: 5.103

5.  A preferred region for recombinational patch repair in the 5' untranslated region of primer binding site-impaired murine leukemia virus vectors.

Authors:  J G Mikkelsen; A H Lund; K D Kristensen; M Duch; M S Sørensen; P Jørgensen; F S Pedersen
Journal:  J Virol       Date:  1996-03       Impact factor: 5.103

6.  The kissing-loop motif is a preferred site of 5' leader recombination during replication of SL3-3 murine leukemia viruses in mice.

Authors:  A H Lund; J G Mikkelsen; J Schmidt; M Duch; F S Pedersen
Journal:  J Virol       Date:  1999-11       Impact factor: 5.103

7.  Point mutants of Moloney murine leukemia virus that fail to package viral RNA: evidence for specific RNA recognition by a "zinc finger-like" protein sequence.

Authors:  R J Gorelick; L E Henderson; J P Hanser; A Rein
Journal:  Proc Natl Acad Sci U S A       Date:  1988-11       Impact factor: 11.205
  7 in total

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