| Literature DB >> 3660349 |
Abstract
The continuous chromogenic tissue factor assay has been compared to one-stage and two-stage coagulation assays, and its sensitivity has been established using purified human placental tissue factor. Log-log plots of the clot-times versus A405/min2 are linear over the mutually useful ranges of tissue factor concentration. Using human placental tissue factor reconstituted into phosphatidylserine-phosphatidylcholine (30:70) vesicles, the chromogenic assay quantitatively detected tissue factor in dilutions containing from 3 femtomoles to less than 10 attomoles of protein.Entities:
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Year: 1987 PMID: 3660349 DOI: 10.1016/0049-3848(87)90453-1
Source DB: PubMed Journal: Thromb Res ISSN: 0049-3848 Impact factor: 3.944