Surface studies of calcium oxalate dihydrate single crystals during dissolution in the presence of urine.

Single crystals of Calcium Oxalate Dihydrate (COD) were grown from solution under controlled release of the reacting ions. Dissolution of COD was studied at different pH levels and in different dilutions of urine. The descriptors of the contour were determined during dissolution of COD using a quantitative morphological technique. The shape parameters and surface ruggedness were determined from Fourier and fractal analysis. The results obtained give quantitative information on the dissolution kinetics and the surface geometry of COD crystals in normal and diluted urine. Dissolution inhibition and morphological changes of COD crystals during dissolution were attributed to selective adsorption of urine non-ionic macromolecules on the crystal stepped surface. Surface etching of COD was found to depend on urine dilution and time of incubation. The data obtained suggest that the geometric structure of the surface is likely to be a potential factor in understanding crystal aggregation in stone formation.