Literature DB >> 3658162

Cerebral blood flow in systemic lupus erythematosus with or without cerebral complications.

M J Kushner1, J Chawluk, F Fazekas, B Mandell, A Burke, J Jaggi, M Rosen, M Reivich.   

Abstract

We measured mean cerebral blood flow (CBF) in 25 lupus patients using the xenon-133 method. The CBF was normal in lupus patients without cerebral disease and also in CNS lupus patients in remission. The CBF was lower than normal during bouts of cerebral lupus (p less than 0.001). Repeat studies showed a stereotyped pattern consisting of depressed CBF during exacerbation of CNS disease and normalization of CBF during remission (p less than 0.01). These results show that CBF is a sensitive indicator of activity of CNS disease and that the direction of change in CBF reflects the clinical course of CNS lupus.

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Year:  1987        PMID： 3658162     DOI： 10.1212/wnl.37.10.1596

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  6 in total

1.  Abnormal brain diffusivity in patients with neuropsychiatric systemic lupus erythematosus.

Authors:  Gerlof P Th Bosma; Tom W J Huizinga; Simon P Mooijaart; Mark A Van Buchem
Journal:  AJNR Am J Neuroradiol       Date:  2003-05       Impact factor: 3.825

Review 2.  Current concepts of neuropsychiatric systemic lupus erythematosus (NP-SLE).

Authors:  R A Asherson; S D Denburg; J A Denburg; R M Carbotte; N Futrell
Journal:  Postgrad Med J       Date:  1993-08       Impact factor: 2.401

3.  Magnetic resonance and computed tomographic imaging in the evaluation of acute neuropsychiatric disease in systemic lupus erythematosus.

Authors:  W L Sibbitt; R R Sibbitt; R H Griffey; C Eckel; A D Bankhurst
Journal:  Ann Rheum Dis       Date:  1989-12       Impact factor: 19.103

4.  Diagnosis and monitoring of central nervous system involvement in systemic lupus erythematosus: value of F-18 fluorodeoxyglucose PET.

Authors:  S M Weiner; A Otte; M Schumacher; R Klein; J Gutfleisch; I Brink; P Otto; E U Nitzsche; E Moser; H H Peter
Journal:  Ann Rheum Dis       Date:  2000-05       Impact factor: 19.103

5.  Single photon emission computed tomography in systemic lupus erythematosus with psychiatric symptoms.

Authors:  K Kodama; S Okada; T Hino; K Takabayashi; Y Nawata; Y Uchida; N Yamanouchi; N Komatsu; T Ikeda; N Shinoda
Journal:  J Neurol Neurosurg Psychiatry       Date:  1995-03       Impact factor: 10.154

6.  Fluctuating cognitive abnormalities and cerebral glucose metabolism in neuropsychiatric systemic lupus erythematosus.

Authors:  R M Carbotte; S D Denburg; J A Denburg; C Nahmias; E S Garnett
Journal:  J Neurol Neurosurg Psychiatry       Date:  1992-11       Impact factor: 10.154
  6 in total

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