Literature DB >> 3657793

Characterization of jacalin, the human IgA and IgD binding lectin from jackfruit.

P Aucouturier1, E Mihaesco, C Mihaesco, J L Preud'homme.   

Abstract

The lectin jacalin from the jackfruit Artocarpus heterophyllus reacts by precipitation and western blotting with human IgA1 and IgD but not with IgA2 (nor IgG and IgM). However, it weakly binds IgA2 as shown by affinity chromatography and competitive ELISA. Predominantly reactive carbohydrates are D-galactose and N-acetyl D-galactosamine. Jacalin has an apparent Mr of about 54,000 and is probably made up of three non-glycosylated and one glycosylated non-covalently linked subunits. Its electrophoretic properties and amino acid and carbohydrate composition are indicated.

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Year:  1987        PMID: 3657793     DOI: 10.1016/0161-5890(87)90025-3

Source DB:  PubMed          Journal:  Mol Immunol        ISSN: 0161-5890            Impact factor:   4.407


  8 in total

1.  Structural and electron-microscopic studies of jacalin from jackfruit (Artocarpus integrifolia) show that this lectin is a 65 kDa tetramer.

Authors:  E Ruffet; N Paquet; S Frutiger; G J Hughes; J C Jaton
Journal:  Biochem J       Date:  1992-08-15       Impact factor: 3.857

Review 2.  The structure and function of human IgA.

Authors:  M A Kerr
Journal:  Biochem J       Date:  1990-10-15       Impact factor: 3.857

3.  Identification of an immunoglobulin A binding motif located in the beta-antigen of the c protein complex of group B streptococci.

Authors:  P G Jerlström; S R Talay; P Valentin-Weigand; K N Timmis; G S Chhatwal
Journal:  Infect Immun       Date:  1996-07       Impact factor: 3.441

4.  Characterization of the peptide-N4-(N-acetylglucosaminyl) asparagine amidase (PNGase Se) from Silene alba cells.

Authors:  S Lhernould; Y Karamanos; P Lerouge; H Morvan
Journal:  Glycoconj J       Date:  1995-02       Impact factor: 2.916

5.  Jacalin: a lectin mitogenic for human CD4 T lymphocytes.

Authors:  N Pineau; P Aucouturier; J C Brugier; J L Preud'homme
Journal:  Clin Exp Immunol       Date:  1990-06       Impact factor: 4.330

6.  Poly-IgA Complexes and Disease Severity in IgA Nephropathy.

Authors:  Xue Zhang; Jicheng Lv; Pan Liu; Xinfang Xie; Manliu Wang; Dan Liu; Hong Zhang; Jing Jin
Journal:  Clin J Am Soc Nephrol       Date:  2021-10-04       Impact factor: 8.237

7.  Domain-swapped structure of the potent antiviral protein griffithsin and its mode of carbohydrate binding.

Authors:  Natasza E Ziółkowska; Barry R O'Keefe; Toshiyuki Mori; Charles Zhu; Barbara Giomarelli; Fakhrieh Vojdani; Kenneth E Palmer; James B McMahon; Alexander Wlodawer
Journal:  Structure       Date:  2006-07       Impact factor: 5.006

8.  Neurodegeneration-associated mutant TREM2 proteins abortively cycle between the ER and ER-Golgi intermediate compartment.

Authors:  Daniel W Sirkis; Renan E Aparicio; Randy Schekman
Journal:  Mol Biol Cell       Date:  2017-08-02       Impact factor: 4.138

  8 in total

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