| Literature DB >> 3657508 |
J A West-Jordan1, A Smith, S Myint, J A Gardner, R J Abraham, R H Edwards, H M Warenius.
Abstract
We describe the use of 31P NMR spectroscopy in the study of metabolic changes related to hypoxia in cultured human tumor cells in vitro. The 31P NMR spectrum can easily distinguish between metabolically active cells, metabolically inactive "dormant" cells, and necrotic cells. A crucial observation was that of the ability of the "dormant" cells to resume active metabolism on incubation with oxygen after long periods of hypoxia.Entities:
Mesh：
Substances：
Year: 1987 PMID： 3657508 DOI： 10.1002/mrm.1910050211
Source DB: PubMed Journal: Magn Reson Med ISSN： 0740-3194 Impact factor: 4.668