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Literature DB >> 365749

Comparison of the histamine hypersensitivity and the Limulus amoebocyte lysate tests for endotoxin activity.

Abstract

The histamine hypersensitivity test and the Limulus amoebocyte lysate test were compared for their effectiveness to quantitate endotoxin activity. The two tests compared favorably in all the trials, except with a sample of endotoxin from Brucella abortus that gave a positive Limulus amoebocyte lysate test at a concentration of 0.001 microgram, while failing to sensitize mice to histamine at a dose of 16 microgram per mouse. The Limulus amoebocyte lysate test was more sensitive than the histamine hypersensitivity test.

Entities: Chemical Disease Species

Mesh：

Substances：
Endotoxins
Histamine

Year: 1978 PMID： 365749 PMCID： PMC422150 DOI： 10.1128/iai.22.1.292-294.1978

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

13 in total

1. THE ROLE OF ENDOTOXIN IN THE EXTRACELLULAR COAGULATION OF LIMULUS BLOOD.

Authors: J LEVIN; F B BANG
Journal: Bull Johns Hopkins Hosp Date: 1964-09

2. Endotoxic and antigenic fractions from the cell wall of Salmonella enteritidis; methods for separation and some biologic activities.

Authors: E RIBI; K C MILNER; T D PERRINE
Journal: J Immunol Date: 1959-01 Impact factor: 5.422

4. Low endotoxic potential of Legionella pneumophila lipopolysaccharide due to failure of interaction with the monocyte lipopolysaccharide receptor CD14.

Authors: B Neumeister; M Faigle; M Sommer; U Zähringer; F Stelter; R Menzel; C Schütt; H Northoff
Journal: Infect Immun Date: 1998-09 Impact factor: 3.441

4 in total

Comparison of the histamine hypersensitivity and the Limulus amoebocyte lysate tests for endotoxin activity.

1. THE ROLE OF ENDOTOXIN IN THE EXTRACELLULAR COAGULATION OF LIMULUS BLOOD.

2. Endotoxic and antigenic fractions from the cell wall of Salmonella enteritidis; methods for separation and some biologic activities.

3. Preparation and properties of a national reference endotoxin.

4. New test for endotoxin potency based upon histamine sensitization in mice.

5. Increased histamine sensitivity in mice after administration of endotoxins.

6. Nonspecificity of the limulus amebocyte lysate test: positive reactions with polynucleotides and proteins.

7. A technique for quantitative measurement of endotoxin in human plasma.

8. Pyrogenicity of poly I. poly C in rabbits.

9. Embryotoxic effect of poly I. poly C.

10. Galactose-sensitive mutants of Salmonella. I. Metabolism of galactose.

Review 1. Pertussis: the disease and new diagnostic methods.

2. Legionella pneumophila and limulus endotoxin assay: recent findings.

3. Purification and characterization of smooth and rough lipopolysaccharides from Brucella abortus.

4. Low endotoxic potential of Legionella pneumophila lipopolysaccharide due to failure of interaction with the monocyte lipopolysaccharide receptor CD14.