Literature DB >> 3655426

[Metastatic thyroid cancer to the right ventricle causing obstruction of the right ventricular outflow tract and associated with disseminated intravascular coagulopathy: a case report].

K Hara1, M Ohno, M Takenaga, H Tsuneyoshi, H Takeuchi, M Kashida, T Yamaguchi, K Machii, S Furuta, E Tohda.   

Abstract

A case of thyroid cancer causing right ventricular outflow tract obstruction is described. A 72-year-old woman was admitted because of shortness of breath, some ecchymoses, and marked anasarca. Her liver was palpable four fingerbreadths below her costal margin. Laboratory findings included leukocytosis, marked thrombocytopenia, and an increase in fibrinogen degradation products due to disseminated intravascular coagulopathy. Two-dimensional echocardiography demonstrated a solid mass in the right ventricle, which protruded into the right atrium and main pulmonary artery. Right ventricular outflow tract obstruction and tricuspid regurgitation were demonstrated by contrast echocardiography. These findings were confirmed by CT scans, RI angiography, and contrast angiography. The mass was partially resected from her right ventricle and her tricuspid valve was replaced successfully, but she died of sepsis three weeks after surgery. At autopsy, undifferentiated thyroid cancer and cardiac metastasis were verified. To date, only eight cases with initial symptoms of congestive heart failure due to right ventricular outflow tract obstruction caused by metastatic intracavitary tumors have been reported. Very rarely have cardiac tumors resulted in disseminated intravascular coagulopathy.

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Year:  1986        PMID: 3655426

Source DB:  PubMed          Journal:  J Cardiogr        ISSN: 0386-2887


  3 in total

1.  Poorly differentiated thyroid carcinoma with cardiac metastasis and pulmonary embolism as first clinical presentation: case report and review of the literature.

Authors:  V Pazzano; M L Narducci; P Santangeli; D Pedicino; F Glieca; C A Rota; M Novello; A Pontecorvi; L Lauriola; F Crea
Journal:  J Endocrinol Invest       Date:  2011-02       Impact factor: 4.256

2.  Cardiac metastasis of squamous cell carcinoma of the thyroid gland with severe disseminated intravascular coagulation: A case report.

Authors:  Tomoyasu Yoshihiro; Kenji Tsuchihashi; Hitoshi Kusaba; Torahiko Nakashima; Teppei Obara; Kenta Nio; Kotoe Takayoshi; Hiroyuki Kodama; Nobuhiro Tsuruta; Hideyuki Kiyohara; Kaori Asai; Eiji Harada; Kenjiro Kamezaki; Takeshi Arita; Masanobu Sato; Hidetaka Yamamoto; Shuji Arita; Hiroshi Ariyama; Keita Odashiro; Yoshinao Oda; Koichi Akashi; Eishi Baba
Journal:  Mol Clin Oncol       Date:  2016-11-23

Review 3.  Right Ventricular Outflow Tract Obstruction in Adults: A Systematic Review and Meta-analysis.

Authors:  Yu Hao Zeng; Alexander Calderone; Nicolas Rousseau-Saine; Mahsa Elmi-Sarabi; Stéphanie Jarry; Étienne J Couture; Matthew P Aldred; Jean-Francois Dorval; Yoan Lamarche; Lachlan F Miles; William Beaubien-Souligny; André Y Denault
Journal:  CJC Open       Date:  2021-04-09
  3 in total

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