Literature DB >> 3653991

Urinary chlorophenols in sawmill workers.

L Lindroos1, H Koskinen, P Mutanen, J Järvisalo.   

Abstract

The concentration of urinary chlorophenol was assayed for 230 sawmill workers. Information on the work tasks was obtained through questionnaires from occupational health centres. The workers were divided into three groups on the basis of the type of exposure: (1) those with skin absorption as the main route, (2) those with skin and respiratory route of equal importance and (3) those with respiratory tract as the main route. The concentrations of urinary chlorophenol were higher in workers with skin absorption as the main route (median concentration: 7.8 mumol l-1; range 0.1 to 210.9 mumol l-1) than in those with both routes of equal importance (1.4 mumol l-1; range 0.1 to 47.8 mumol l-1, P less than 0.001) or in those with mainly respiratory route (0.9 mumol l-1; range 0.1 to 13.3 mumol l-1, P less than 0.001). The urinary chlorophenol concentration was below 15 mumol l-1 in all workers with the lungs as the main absorption route. In nine out of 112 workers whose main absorption route was the skin, the urinary chlorophenol values were above 50 mumol l-1. Six were loaders when the through-dipping method was used. In two of them urinary chlorophenol concentrations were as high as 170.8 and 210.9 mumol l-1. These results emphasize the need to develop and use simple methods of protection against skin contact with chlorophenols.

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Year:  1987        PMID: 3653991     DOI: 10.1007/BF00377840

Source DB:  PubMed          Journal:  Int Arch Occup Environ Health        ISSN: 0340-0131            Impact factor:   3.015


  7 in total

1.  Tropical hazards associated with the use of pentachlorophenol.

Authors:  J A MENON
Journal:  Br Med J       Date:  1958-05-17

2.  [Studies on toxicology of pentachlorophenol. II. Occupational poisoning in the wood processing industry; reports of two fatal cases].

Authors:  R TRUHAUT; P L'EPEE; E BOUSSEMART
Journal:  Arch Mal Prof       Date:  1952

3.  Percutaneous absorption of m-xylene in man.

Authors:  K Engström; K Husman; V Riihimäki
Journal:  Int Arch Occup Environ Health       Date:  1977-08-31       Impact factor: 3.015

4.  Skin absorption of toluene, styrene, and xylene by man.

Authors:  T Dutkiewicz; H Tyras
Journal:  Br J Ind Med       Date:  1968-07

5.  Bioassay of 2,4,6-trichlorophenol for possible carcinogenicity.

Authors: 
Journal:  Natl Cancer Inst Carcinog Tech Rep Ser       Date:  1979

6.  Percutaneous absorption of solvent vapors in man.

Authors:  V Riihimäki; P Pfäffli
Journal:  Scand J Work Environ Health       Date:  1978-03       Impact factor: 5.024

7.  Chlorophenol exposure in sawmills.

Authors:  T Kauppinen; L Lindroos
Journal:  Am Ind Hyg Assoc J       Date:  1985-01
  7 in total
  1 in total

1.  Pentachlorophenol-induced cytotoxicity in human erythrocytes: enhanced generation of ROS and RNS, lowered antioxidant power, inhibition of glucose metabolism, and morphological changes.

Authors:  Nikhil Maheshwari; Fahim Halim Khan; Riaz Mahmood
Journal:  Environ Sci Pollut Res Int       Date:  2019-03-20       Impact factor: 4.223

  1 in total

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