Literature DB >> 3653757

Twenty four hour oesophageal acidity in achalasia before and after pneumatic dilatation.

H L Smart1, P N Foster, D F Evans, B Slevin, M Atkinson.   

Abstract

Radiotelemetric ambulatory 24 hour oesophageal pH measurement was carried out in 17 patients with symptomatic manometrically proven achalasia before and after pneumatic dilatation. Before dilatation an abnormally high percentage acid exposure time was present but typical episodes of gastro-oesophageal reflux occurred in only one patient. In nine patients who had a oesophageal food residue these values were significantly greater than those found in the remaining patients without retained food. Analysis of oesophageal food residues revealed that the low pH was predominantly caused by lactic acid. These findings indicate that preoperative oesophageal pH studies do not offer a valid means of selection of patients in whom an antireflux procedure should be combined with cardiomyotomy. Repeat studies one week after pneumatic dilatation showed a fall in the acid exposure time in patients with initial food residue presumably resulting from improved oesophageal emptying after treatment. A significant rise in acid exposure time after dilatation was seen in those patients without initial food residue presumably resulting from gastro-oesophageal reflux after therapeutic disruption of the lower oesophageal sphincter. Troublesome symptoms of gastro-oesophageal reflux were, however, uncommon after bag dilatation.

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Year:  1987        PMID: 3653757      PMCID: PMC1433080          DOI: 10.1136/gut.28.7.883

Source DB:  PubMed          Journal:  Gut        ISSN: 0017-5749            Impact factor:   23.059


  8 in total

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Journal:  N Engl J Med       Date:  1965-04-01       Impact factor: 91.245

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Journal:  Am J Surg       Date:  1974-12       Impact factor: 2.565

3.  To dilate or to operate? That is the question.

Authors:  G Vantrappen; J Janssens
Journal:  Gut       Date:  1983-11       Impact factor: 23.059

4.  A frequency-duration index (FDI) for the evaluation of ambulatory recordings of gastro-oesophageal reflux.

Authors:  F J Branicki; D F Evans; J A Jones; A L Ogilvie; M Atkinson; J D Hardcastle
Journal:  Br J Surg       Date:  1984-06       Impact factor: 6.939

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Authors:  M Atkinson; M D Summerling
Journal:  Gut       Date:  1966-08       Impact factor: 23.059

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Authors:  S Björck; L Dernevik; P Gatzinsky; N Sandberg
Journal:  Acta Chir Scand       Date:  1982

7.  Pneumatic dilatation in achalasia.

Authors:  I W Fellows; A L Ogilvie; M Atkinson
Journal:  Gut       Date:  1983-11       Impact factor: 23.059

8.  Achalasia following gastro-oesophageal reflux.

Authors:  H L Smart; J F Mayberry; M Atkinson
Journal:  J R Soc Med       Date:  1986-02       Impact factor: 5.344

  8 in total
  22 in total

1.  Management of dysphagia in suspected esophageal motor disorders.

Authors:  N Bourgeois; M Coffernils; M Buset; M Gelin; M Deltenre; J M Panzer; M Cremer
Journal:  Dig Dis Sci       Date:  1991-03       Impact factor: 3.199

2.  Heartburn in patients with achalasia.

Authors:  S J Spechler; R F Souza; S J Rosenberg; R A Ruben; R K Goyal
Journal:  Gut       Date:  1995-09       Impact factor: 23.059

3.  Reproducibility of ambulatory esophageal pH monitoring in the aperistaltic esophagus.

Authors:  J P Shoenut; A B Mieflikier; T A Aldor; C S Yaffe; D J Goldenberg
Journal:  Dysphagia       Date:  1996       Impact factor: 3.438

4.  Ambulatory esophageal pH monitoring in patients with motility disorders.

Authors:  P F Crookes; T R DeMeester
Journal:  Dysphagia       Date:  1996       Impact factor: 3.438

5.  Gastroesophageal reflux in achalasia. When is reflux really reflux?

Authors:  P F Crookes; S Corkill; T R DeMeester
Journal:  Dig Dis Sci       Date:  1997-07       Impact factor: 3.199

6.  High prevalence of heartburn and low acid sensitivity in patients with idiopathic achalasia.

Authors:  Julio Ponce; Vicente Ortiz; Nuria Maroto; Marta Ponce; Marco Bustamante; Vicente Garrigues
Journal:  Dig Dis Sci       Date:  2010-07-30       Impact factor: 3.199

7.  Effect of pneumatic dilation on gastroesophageal reflux in achalasia.

Authors:  C A Burke; E Achkar; G W Falk
Journal:  Dig Dis Sci       Date:  1997-05       Impact factor: 3.199

8.  Failure of transient lower oesophageal sphincter relaxation in response to gastric distension in patients with achalasia: evidence for neural mediation of transient lower oesophageal sphincter relaxations.

Authors:  R H Holloway; J B Wyman; J Dent
Journal:  Gut       Date:  1989-06       Impact factor: 23.059

9.  Importance of preoperative and postoperative pH monitoring in patients with esophageal achalasia.

Authors:  M G Patti; M Arcerito; J Tong; A Wang; C V Feo; S J Mulvihill; L W Way
Journal:  J Gastrointest Surg       Date:  1997 Nov-Dec       Impact factor: 3.452

10.  Current clinical approach to achalasia.

Authors:  Alexander J Eckardt; Volker F Eckardt
Journal:  World J Gastroenterol       Date:  2009-08-28       Impact factor: 5.742

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