Monitoring follicular maturation through measurement of urinary estrogen excretion by latex agglutination inhibition reaction.

We evaluated the clinical utility of the MS 8601 kit, which is a new method of measurement of estrogens in urine. Changes in daily urinary estrogen excretion measured with the kit were highly correlated with that in daily serum E2. This kit was sensitive enough to detect the rises in estrogens in the follicular phase not only in women with normal menstrual cycle, but also in hMG-hCG treated patients.