Literature DB >> 3653145

Blood-cerebrospinal fluid barrier in schizophrenic patients.

K Bauer1, J Kornhuber.   

Abstract

A total of 15 young white male patients newly diagnosed as schizophrenic (DMS III) were examined for signs of blood-cerebrospinal fluid (CSF) barrier alteration and CNS IgG synthesis. Of the 15 patients, 8 exhibited signs of increased blood-CSF barrier permeability. There was a high correlation between the ratio for CSF/serum albumin concentration and the CSF total protein concentration. Local IgG synthesis in the CNS was not detected in any of the patients.

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Year:  1987        PMID: 3653145     DOI: 10.1007/BF00380949

Source DB:  PubMed          Journal:  Eur Arch Psychiatry Neurol Sci        ISSN: 0175-758X


  21 in total

1.  [Disorder of the blood-brain barrier in schizophrenia].

Authors:  J Kornhuber; K Bauer
Journal:  Dtsch Med Wochenschr       Date:  1986-06-27       Impact factor: 0.628

2.  Principles of albumin and IgG analyses in neurological disorders. I. Establishment of reference values.

Authors:  G Tibbling; H Link; S Ohman
Journal:  Scand J Clin Lab Invest       Date:  1977-09       Impact factor: 1.713

3.  The origin and turnover rates of cerebrospinal fluid albumin and gamma-globulin in man.

Authors:  R W Cutler; G V Watters; J P Hammerstad
Journal:  J Neurol Sci       Date:  1970-03       Impact factor: 3.181

4.  Viruses and schizophrenia.

Authors:  C A Kaufmann; D R Weinberger; R H Yolken; E F Torrey; S G Pofkin
Journal:  Lancet       Date:  1983-11-12       Impact factor: 79.321

5.  Immunoglobulin studies in patients with psychiatric diseases.

Authors:  R P Roos; K Davis; H Y Meltzer
Journal:  Arch Gen Psychiatry       Date:  1985-02

6.  Quantitative determination of immunoglobulins in CSF and plasma of chronic schizophrenic patients.

Authors:  L E Delisi; D R Weinberger; S Potkin; L M Neckers; D J Shiling; R J Wyatt
Journal:  Br J Psychiatry       Date:  1981-12       Impact factor: 9.319

7.  Evidence of disturbed CSF circulation and brain atrophy in cases of schizophrenic psychosis.

Authors:  G Oxenstierna; G Bergstrand; L Bjerkenstedt; G Sedvall; G Wik
Journal:  Br J Psychiatry       Date:  1984-06       Impact factor: 9.319

8.  [Calculation of the IgG fraction of cerebrospinal fluid locally synthesized in the central nervous system (author's transl)].

Authors:  H Reiber
Journal:  J Clin Chem Clin Biochem       Date:  1979-09

9.  Immunoglobulins and viral antibodies in psychiatric patients.

Authors:  E F Toorey; M R Peterson; W L Brannon; W T Carpenter; R M Post; D P Van Kammen
Journal:  Br J Psychiatry       Date:  1978-04       Impact factor: 9.319

Review 10.  Is schizophrenia an autoimmune disease? A review.

Authors:  J G Knight
Journal:  Methods Find Exp Clin Pharmacol       Date:  1984-07
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  16 in total

Review 1.  Cerebrospinal fluid biomarker candidates of schizophrenia: where do we stand?

Authors:  Nenad Vasic; Bernhard J Connemann; Robert C Wolf; Hayrettin Tumani; Johannes Brettschneider
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2011-12-16       Impact factor: 5.270

Review 2.  The Gut Microbiota and the Emergence of Autoimmunity: Relevance to Major Psychiatric Disorders.

Authors:  Emily G Severance; Dag Tveiten; Lief H Lindström; Robert H Yolken; Karl L Reichelt
Journal:  Curr Pharm Des       Date:  2016       Impact factor: 3.116

3.  Impaired copper transport in schizophrenia results in a copper-deficient brain state: A new side to the dysbindin story.

Authors:  Kirsten E Schoonover; Stacy L Queern; Suzanne E Lapi; Rosalinda C Roberts
Journal:  World J Biol Psychiatry       Date:  2018-12-20       Impact factor: 4.132

Review 4.  Gastroenterology issues in schizophrenia: why the gut matters.

Authors:  Emily G Severance; Emese Prandovszky; James Castiglione; Robert H Yolken
Journal:  Curr Psychiatry Rep       Date:  2015-05       Impact factor: 5.285

Review 5.  Viruses, schizophrenia, and bipolar disorder.

Authors:  R H Yolken; E F Torrey
Journal:  Clin Microbiol Rev       Date:  1995-01       Impact factor: 26.132

6.  Blood-CSF barrier permeability and central nervous system immunoglobulin G in schizophrenia.

Authors:  D G Kirch; R C Alexander; R L Suddath; N M Papadopoulos; C A Kaufmann; D G Daniel; R J Wyatt
Journal:  J Neural Transm Gen Sect       Date:  1992

7.  IgG dynamics of dietary antigens point to cerebrospinal fluid barrier or flow dysfunction in first-episode schizophrenia.

Authors:  Emily G Severance; Kristin L Gressitt; Armin Alaedini; Cathrin Rohleder; Frank Enning; J Malte Bumb; Juliane K Müller; Emanuel Schwarz; Robert H Yolken; F Markus Leweke
Journal:  Brain Behav Immun       Date:  2014-09-20       Impact factor: 7.217

8.  Interactions between knockout of schizophrenia risk factor Dysbindin-1 and copper metabolism in mice.

Authors:  Kirsten E Schoonover; Laura J McMeekin; Charlene B Farmer; Neelu E Varghese; Stacy L Queern; Suzanne E Lapi; Rita M Cowell; Rosalinda C Roberts
Journal:  Brain Res Bull       Date:  2020-08-12       Impact factor: 4.077

Review 9.  Not Just a Bystander: The Emerging Role of Astrocytes and Research Tools in Studying Cognitive Dysfunctions in Schizophrenia.

Authors:  Chia-Yuan Chang; Da-Zhong Luo; Ju-Chun Pei; Ming-Che Kuo; Yi-Chen Hsieh; Wen-Sung Lai
Journal:  Int J Mol Sci       Date:  2021-05-19       Impact factor: 5.923

10.  Microscopic particles in two fractions of fresh cerebrospinal fluid in twins with schizophrenia or bipolar disorder and in healthy controls.

Authors:  Viktoria Johansson; Rolf Nybom; Lennart Wetterberg; Christina M Hultman; Tyrone D Cannon; Anette G M Johansson; Carl Johan Ekman; Mikael Landén
Journal:  PLoS One       Date:  2012-09-25       Impact factor: 3.240

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