Literature DB >> 3651175

2',3'-Dideoxy-2'-fluoro-ara-A. An acid-stable purine nucleoside active against human immunodeficiency virus (HIV).

V E Marquez, C K Tseng, J A Kelley, H Mitsuya, S Broder, J S Roth, J S Driscoll.   

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Year:  1987        PMID： 3651175     DOI： 10.1016/0006-2952(87)90254-1

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN： 0006-2952            Impact factor:   5.858


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  12 in total

1.  Synthesis and antiviral activity of purine 2',3'-dideoxy-2',3'-difluoro-D-arabinofuranosyl nucleosides.

Authors:  Grigorii G Sivets; Elena N Kalinichenko; Igor A Mikhailopulo; Mervi A Detorio; Tami R McBrayer; Tony Whitaker; Raymond F Schinazi
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2009-05       Impact factor: 1.381

2.  In vitro induction of human immunodeficiency virus type 1 variants resistant to 2'-beta-Fluoro-2',3'-dideoxyadenosine.

Authors:  M Tanaka; R V Srinivas; T Ueno; M F Kavlick; F K Hui; A Fridland; J S Driscoll; H Mitsuya
Journal:  Antimicrob Agents Chemother       Date:  1997-06       Impact factor: 5.191

3.  Role of brain tissue localized purine metabolizing enzymes in the central nervous system delivery of anti-HIV agents 2'-beta-fluoro-2',3'-dideoxyinosine and 2'-beta-fluoro-2',3'-dideoxyadenosine in rats.

Authors:  D Singhal; M E Morgan; B D Anderson
Journal:  Pharm Res       Date:  1997-06       Impact factor: 4.200

4.  Potent activity of 2'-beta-fluoro-2',3'-dideoxyadenosine against human immunodeficiency virus type 1 infection in hu-PBL-SCID mice.

Authors:  K Ruxrungtham; E Boone; H Ford; J S Driscoll; R T Davey; H C Lane
Journal:  Antimicrob Agents Chemother       Date:  1996-10       Impact factor: 5.191

5.  Extensive absorption of 2',3'-dideoxyinosine by intratracheal administration in rats.

Authors:  X Gao; M G Wientjes; J L Au
Journal:  Pharm Res       Date:  1995-12       Impact factor: 4.200

6.  Single dose and multiple dose pharmacokinetics of 2'-fluoro-2',3'-dideoxyadenosine and 2'-fluoro-2',3'-dideoxyinosine, anti-HIV agents, in rats.

Authors:  N R Srinivas; W C Shyu
Journal:  Eur J Drug Metab Pharmacokinet       Date:  1999 Oct-Dec       Impact factor: 2.441

7.  Structure-activity relationships of fluorinated nucleoside analogs and their synergistic effect in combination with phosphonoformate against human immunodeficiency virus type 1.

Authors:  R Koshida; S Cox; J Harmenberg; G Gilljam; B Wahren
Journal:  Antimicrob Agents Chemother       Date:  1989-12       Impact factor: 5.191

Review 8.  Metabolism and mechanism of antiretroviral action of purine and pyrimidine derivatives.

Authors:  J Balzarini
Journal:  Pharm World Sci       Date:  1994-04-15

9.  Percutaneous absorption of 2',3'-dideoxyinosine in rats.

Authors:  E Mukherji; N J Millenbaugh; J L Au
Journal:  Pharm Res       Date:  1994-06       Impact factor: 4.200

10.  Oral antilymphocyte activity and induction of apoptosis by 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine.

Authors:  D A Carson; D B Wasson; L M Esparza; C J Carrera; T J Kipps; H B Cottam
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-01       Impact factor: 11.205
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