Literature DB >> 3644371

Effect of human urinary trypsin inhibitor on granulocyte elastase activity.

M Ogawa, S Nishibe, T Mori, S Neumann.   

Abstract

A human urinary trypsin inhibitor preparation, MR-20, strongly inhibited granulocyte elastase activity. The concentration of MR-20 causing 50% inhibition of the hydrolysis of Suc(Ala) 3pNA by granulocyte elastase was estimated to be 6.4 X 10(-8) M (11 U/ml).

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Year:  1987        PMID: 3644371

Source DB:  PubMed          Journal:  Res Commun Chem Pathol Pharmacol        ISSN: 0034-5164


  11 in total

1.  Ulinastatin reduces elevation of cytokines and soluble adhesion molecules during cardiac surgery.

Authors:  T Kawamura; K Inada; N Akasaka; R Wakusawa
Journal:  Can J Anaesth       Date:  1996-05       Impact factor: 5.063

2.  Use of a protease inhibitor, ulinastatin, for reexpansion pulmonary edema following evacuation of bilateral pleural effusion.

Authors:  S Yamada; Y Nishida; K Yamazaki; H Kato
Journal:  J Anesth       Date:  1994-09       Impact factor: 2.078

3.  Intra-alveolar urinary trypsin inhibitor cannot inhibit polymorphonuclear elastase activity in the lung in postsurgical patients with acute respiratory distress syndrome.

Authors:  M Nakane; H Iwama
Journal:  Surg Today       Date:  1999       Impact factor: 2.549

4.  Determination of urinary trypsin inhibitor provides insight into postoperative complications in patients following esophagectomy.

Authors:  Ichiro Akagi; Masao Miyashita; Ken Takahashi; Takeshi Matsutani; Akihisa Matsuda; Tsutomu Nomura; Hiroshi Makino; Nobutoshi Hagiwara; Eiji Uchida
Journal:  Exp Ther Med       Date:  2012-04-18       Impact factor: 2.447

5.  Ulinastatin therapy in kawasaki disease.

Authors:  Satoru Iwashima; Masashi Seguchi; Tadashi Matubayashi; Takehiko Ohzeki
Journal:  Clin Drug Investig       Date:  2007       Impact factor: 2.859

6.  Lung microvascular endothelial cell injury caused by treatment with polymorphonuclear neutrophils and low-IgM serum: a model of transfusion-related acute lung injury.

Authors:  Motoko Nishimura; Minoko Takanashi; Hitoshi Okazaki; Masahiro Satake
Journal:  Lung       Date:  2006 Jan-Feb       Impact factor: 3.777

7.  The anti-inflammatory effects of ulinastatin in trauma patients with hemorrhagic shock.

Authors:  Kyung Hye Park; Kang Hyun Lee; Hyun Kim; Sung Oh Hwang
Journal:  J Korean Med Sci       Date:  2009-12-26       Impact factor: 2.153

8.  Characterization and pharmacological properties of a novel multifunctional Kunitz inhibitor from Erythrina velutina seeds.

Authors:  Richele J A Machado; Norberto K V Monteiro; Ludovico Migliolo; Osmar N Silva; Michele F S Pinto; Adeliana S Oliveira; Octávio L Franco; Sumika Kiyota; Marcelo P Bemquerer; Adriana F Uchoa; Ana H A Morais; Elizeu A Santos
Journal:  PLoS One       Date:  2013-05-28       Impact factor: 3.240

9.  Effects of ulinastatin on postoperative blood loss and hemostasis in atrioventricular valve surgery with cardiopulmonary bypass.

Authors:  Jae Bum Park; Seong Hyop Kim; Song Am Lee; Jin Woo Chung; Jun Seok Kim; Hyun Keun Chee
Journal:  Korean J Thorac Cardiovasc Surg       Date:  2013-06-05

10.  Protective effects of urinary trypsin inhibitor on systemic inflammatory response induced by lipopolysaccharide.

Authors:  Ken-Ichiro Inoue; Hirohisa Takano; Rie Yanagisawa; Toshikazu Yoshikawa
Journal:  J Clin Biochem Nutr       Date:  2008-10-31       Impact factor: 3.114

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