Literature DB >> 363727

Fibroblasts and macrophages of mice with the Chediak-Higashi-like syndrome have microtubules and actin cables.

F R Frankel, R W Tucker, J Bruce, R Stenberg.   

Abstract

Cells of the beige mouse contain abnormally large lysosomes and show enhanced capping of concanavalin A. It has been suggested that these phenomena may be secondary to a defect in microtubule polymerization. We have examined the cytoskeleton of beige mouse cells by indirect immunofluorescence and find the number and distribution of microtubules and actin cables to be indistinguishable from those of normal control cells.

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Year:  1978        PMID： 363727      PMCID： PMC2110259          DOI： 10.1083/jcb.79.2.401

Source DB:  PubMed          Journal:  J Cell Biol        ISSN： 0021-9525            Impact factor:   10.539


  2 in total

1.  Muscle-like contractile proteins and tubulin in synaptosomes.

Authors:  A L Blitz; R E Fine
Journal:  Proc Natl Acad Sci U S A       Date:  1974-11       Impact factor: 11.205

2.  Correction of characteristic abnormalities of microtubule function and granule morphology in Chediak-Higashi syndrome with cholinergic agonists.

Authors:  J M Oliver; R B Zurier
Journal:  J Clin Invest       Date:  1976-05       Impact factor: 14.808
  2 in total
  11 in total

1.  Enlarged dysmorphic lysosomes in an established beige (C57BL/6J;bgJ(/bgJ)) mouse mutant fibroblast line: a reversible characteristic.

Authors:  J B Gow; T A Lyerla; S Lainwala
Journal:  In Vitro Cell Dev Biol Anim       Date:  1996-09       Impact factor: 2.416

2.  Hidradenitis suppurativa: evidence for a bactericidal defect correctable by cholinergic agonist in vitro and in vivo.

Authors:  P A Ginder; M Ousley; D Hinthorn; C Liu; N I Abdou
Journal:  J Clin Immunol       Date:  1982-07       Impact factor: 8.317

3.  Cellular expression of the beige mouse mutation and its correction in hybrids with control human fibroblasts.

Authors:  J B Gow; S Lainwala; T A Lyerla
Journal:  In Vitro Cell Dev Biol Anim       Date:  1993-11       Impact factor: 2.416

Review 4.  The role of cytoskeletal and cytocontractile elements in pathologic processes.

Authors:  E Rungger-Brändle; G Gabbiani
Journal:  Am J Pathol       Date:  1983-03       Impact factor: 4.307

5.  Altered secretion of kidney lysosomal enzymes in the mouse pigment mutants ruby-eye, ruby-eye-2-J, and maroon.

Authors:  E K Novak; F Wieland; G P Jahreis; R T Swank
Journal:  Biochem Genet       Date:  1980-06       Impact factor: 1.890

6.  Ultrastructure of resting and activated storage pool deficient platelets from animals with the Chédiak-Higashi syndrome.

Authors:  K M Meyers; G Hopkins; H Holmsen; K Benson; D J Prieur
Journal:  Am J Pathol       Date:  1982-03       Impact factor: 4.307

7.  Giant dense bodies in fibroblasts cultured from beige mice with the Chédiak-Higashi syndrome.

Authors:  R A Vincent; S S Spicer
Journal:  Am J Pathol       Date:  1981-12       Impact factor: 4.307

8.  Pseudomonas fluorescens alters epithelial permeability and translocates across Caco-2/TC7 intestinal cells.

Authors:  Amar Madi; Pascal Svinareff; Nicole Orange; Marc Gj Feuilloley; Nathalie Connil
Journal:  Gut Pathog       Date:  2010-11-27       Impact factor: 4.181

9.  Deficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndrome.

Authors:  W Faigle; G Raposo; D Tenza; V Pinet; A B Vogt; H Kropshofer; A Fischer; G de Saint-Basile; S Amigorena
Journal:  J Cell Biol       Date:  1998-06-01       Impact factor: 10.539

10.  Tubulin tyrosinolation in human polymorphonuclear leukocytes: studies in normal subjects and in patients with the Chediak-Higashi syndrome.

Authors:  J Nath; M Flavin; J I Gallin
Journal:  J Cell Biol       Date:  1982-11       Impact factor: 10.539
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