Literature DB >> 363493

Obesity: do fat cells from genetically obese mice (C57BL/6J ob/ob) have an innate capacity for increased fat storage?

M Ashwell, C J Meade.   

Abstract

Fat tissue from the genetically obese mouse (C57BL/6J ob/ob) and its lean littermate (+/?) was transplanted into lean hosts(+/+). Chemical induced obesity in the host mice caused no greater increase in the size of 'obese' fat cells than it did in the size of 'lean' fat cells. 'Obese' fat cells, therefore, have no innate capacity for increased fat storage.

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Year:  1978        PMID： 363493     DOI： 10.1007/bf02342871

Source DB:  PubMed          Journal:  Diabetologia        ISSN： 0012-186X            Impact factor:   10.122


  13 in total

1.  Obesity in albino mice due to single injections of goldthioglucose.

Authors:  G BRECHER; S H WAXLER
Journal:  Proc Soc Exp Biol Med       Date:  1949-03

2.  Lipoprotein lipase activities in tissues of normal and genetically obese (ob-ob) mice.

Authors:  E A Rath; D A Hems; A Beloff-Chain
Journal:  Diabetologia       Date:  1974-08       Impact factor: 10.122

3.  Role of the thyroid in the development of the obese-hyperglycemic syndrome in mice (ob ob).

Authors:  H F Joosten; P H van der Kroon
Journal:  Metabolism       Date:  1974-05       Impact factor: 8.694

4.  Thermogenic defect in pre-obese ob/ob mice.

Authors:  P Trayhurn; P L Thurlby; W P James
Journal:  Nature       Date:  1977-03-03       Impact factor: 49.962

5.  Adipose tissue: contributions of nature and nurture to the obesity of an obese mutant mouse (ob/ob).

Authors:  M Ashwell; C J Meade; P Medawar; C Sowter
Journal:  Proc R Soc Lond B Biol Sci       Date:  1977-01-14

6.  The development of obesity in preweaning obob mice.

Authors:  P L Thurlby; P Trayhurn
Journal:  Br J Nutr       Date:  1978-03       Impact factor: 3.718

7.  Cellularity of adipose depots in six strains of genetically obese mice.

Authors:  P R Johnson; J Hirsch
Journal:  J Lipid Res       Date:  1972-01       Impact factor: 5.922

8.  Human fat cell sizing--a quick, simple method.

Authors:  M Ashwell; P Priest; M Bondoux; C Sowter; C K McPherson
Journal:  J Lipid Res       Date:  1976-03       Impact factor: 5.922

9.  An enzymatic defect in the obese (ob/ob) mouse: loss of thyroid-induced sodium- and potassium-dependent adenosinetriphosphatase.

Authors:  D A York; G A Bray; Y Yukimura
Journal:  Proc Natl Acad Sci U S A       Date:  1978-01       Impact factor: 11.205

10.  Lowered oxygen consumption and heart rate as early symptoms of the obese-hyperglycemic syndrome in mice (ob/ob).

Authors:  H W van der Kroon; T M van Vroonhoven; L T Douglas
Journal:  Int J Obes       Date:  1977
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  7 in total

1.  In vivo evidence for unidentified leptin-induced circulating factors that control white fat mass.

Authors:  Ruth B S Harris
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2015-10-14       Impact factor: 3.619

Review 2.  Control of energy homeostasis by amylin.

Authors:  Thomas A Lutz
Journal:  Cell Mol Life Sci       Date:  2011-12-23       Impact factor: 9.261

Review 3.  Gut hormones such as amylin and GLP-1 in the control of eating and energy expenditure.

Authors:  T A Lutz
Journal:  Int J Obes Suppl       Date:  2016-11-16

4.  Fatty acid composition of triglycerides from adipose tissue transplanted between obese and lean mice.

Authors:  M Enser; M Ashwell
Journal:  Lipids       Date:  1983-11       Impact factor: 1.880

5.  Establishment of a preadipocyte cell line from the epididymal fat pad of the lean C57 BL/6J mouse--long term effects of insulin and triiodothyronine on adipose conversion.

Authors:  C Forest; P Grimaldi; D Czerucka; R Negrel; G Ailhaud
Journal:  In Vitro       Date:  1983-04

6.  Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus.

Authors:  M Maffei; H Fei; G H Lee; C Dani; P Leroy; Y Zhang; R Proenca; R Negrel; G Ailhaud; J M Friedman
Journal:  Proc Natl Acad Sci U S A       Date:  1995-07-18       Impact factor: 11.205

Review 7.  A Systematic Scoping Review of Surgically Manipulated Adipose Tissue and the Regulation of Energetics and Body Fat in Animals.

Authors:  Anarina L Murillo; Kathryn A Kaiser; Daniel L Smith; Courtney M Peterson; Olivia Affuso; Hemant K Tiwari; David B Allison
Journal:  Obesity (Silver Spring)       Date:  2019-07-30       Impact factor: 5.002
  7 in total

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