Literature DB >> 363418

How operant conditioning can contribute to behavioral toxicology.

V G Laties.   

Abstract

Operant conditioning can contribute to the development of behavioral toxicology in many ways. Its techniques are useful in training animals in the various behaviors the toxicologist may wish to study. They make possible the sophisticated assessment of sensory functioning. Operant conditioners excel at using schedules of intermittent reinforcement to create the type of stable animal performance needed in studying substances that produce effects only after prolonged exposure. Schedule-controlled behavior also helps elucidate the precise behavioral mechanisms involved in toxicity. In the early assessment of toxic substances a judiciously chosen sample of schelule-controlled performances may provide the best estimate whether the integrity of complex operant behavior remains unchanged. The development of improved behavioral techniques and computer technology promises to bring down the cost of such assessment.

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Year:  1978        PMID: 363418      PMCID: PMC1637251          DOI: 10.1289/ehp.782629

Source DB:  PubMed          Journal:  Environ Health Perspect        ISSN: 0091-6765            Impact factor:   9.031


  34 in total

1.  The repeated acquisition of behavioral chains.

Authors:  J J Boren; D D Devine
Journal:  J Exp Anal Behav       Date:  1968-11       Impact factor: 2.468

2.  Schedule-induced chronic hypertension.

Authors:  J L Fak; M Tang; S Forman
Journal:  Psychosom Med       Date:  1977 Jul-Aug       Impact factor: 4.312

3.  Nitrous oxide self-administration by the squirrel monkey.

Authors:  R W Wood; J Grubman; B Weiss
Journal:  J Pharmacol Exp Ther       Date:  1977-09       Impact factor: 4.030

4.  Chronic effects of lead on schedule-controlled pigeon behavior.

Authors:  G T Barthalmus; J D Leander; D E McMillan; P Mushak; M R Krigman
Journal:  Toxicol Appl Pharmacol       Date:  1977-11       Impact factor: 4.219

5.  Chronic mercuric chloride: Behavioral effects in pigeons.

Authors:  J D Leander; D E McMillan; T S Barlow
Journal:  Environ Res       Date:  1977-12       Impact factor: 6.498

6.  Epistemology of screening for behavioral toxicity.

Authors:  P B Dews
Journal:  Environ Health Perspect       Date:  1978-10       Impact factor: 9.031

Review 7.  Behavioral assessment of visual toxicity.

Authors:  H L Evans
Journal:  Environ Health Perspect       Date:  1978-10       Impact factor: 9.031

8.  Electrical self-stimulation of the brain: a model for the behavioral evaluation of toxic agents.

Authors:  Z Annau
Journal:  Environ Health Perspect       Date:  1978-10       Impact factor: 9.031

Review 9.  Stimulus properties of inhaled substances.

Authors:  R W Wood
Journal:  Environ Health Perspect       Date:  1978-10       Impact factor: 9.031

10.  Behavioral ototoxicology.

Authors:  W C Stebbins; M C Rudy
Journal:  Environ Health Perspect       Date:  1978-10       Impact factor: 9.031

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  2 in total

1.  Learning behavior in rat offspring after in utero and lactational exposure to either TCDD or PCB126.

Authors:  Rieko Hojo; Masaki Kakeyama; Yoshika Kurokawa; Yasunobu Aoki; Junzo Yonemoto; Chiharu Tohyama
Journal:  Environ Health Prev Med       Date:  2008-03-29       Impact factor: 3.674

2.  Use of operant performance to guide and evaluate medical treatment in an adult male cynomolgus macaque (Macaca fascicularis).

Authors:  Lindsey R Hamilton; David M Cox; Todd M Myers
Journal:  J Am Assoc Lab Anim Sci       Date:  2011-11       Impact factor: 1.232

  2 in total

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