Chronic nephritis in a horse.

An 11 year old Anglo-Arabian mare was presented with a five month history of gradual weight loss and inappetence. On physical examination the mare was in fair body condition with no localising signs of illness. Persistently elevated blood urea nitrogen and isothenuria indicated the presence of primary renal failure. At necropsy both kidneys were shrunken and contracted. Histopathology revealed lesions consistent with end stage renal disease which were characterised by severe and diffuse interstitial fibrosis.