Literature DB >> 3631762

Radiation enteritis.

P H O'Brien, J M Jenrette, A J Garvin.   

Abstract

As the population receiving radiation therapy grows, so does the incidence of chronic radiation enteritis. A review of the pathology of chronic radiation enteritis reveals fibrosis, endarteritis, edema, fragility, perforation, and partial obstruction. Conservative management of patients with this disease is common. Because the obstruction is only partial, decompression is easily achieved with nasogastric suction and parenteral support. The patient is then often discharged on a liquid-to-soft diet. This therapeutic strategy does nothing for the underlying pathology. The problem, sooner or later, will return with the patient further depleted by the chronic radiation enteritis. We think surgical intervention is appropriate when the diagnosis of chronic radiation enteritis is assumed. The surgery in relation to this disease is high risk with a 30% mortality and 100% expensive morbidity. Early intervention seems to decrease these figures. All anastomoses, if possible, should be outside the irradiated area. Trapped pelvic loops of intestine should be left in place and a bypass procedure with decompressing enterostomies accomplished. The surgery should be performed by a surgeon with extensive experience with all kinds of bowel obstruction as well as experience in performing surgery in radiated tissue.

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Year:  1987        PMID: 3631762

Source DB:  PubMed          Journal:  Am Surg        ISSN: 0003-1348            Impact factor:   0.688


  4 in total

1.  Small bowel toxicity after high dose spot scanning-based proton beam therapy for paraspinal/retroperitoneal neoplasms.

Authors:  R A Schneider; V Vitolo; F Albertini; T Koch; C Ares; A Lomax; G Goitein; E B Hug
Journal:  Strahlenther Onkol       Date:  2013-09-21       Impact factor: 3.621

2.  Recent advances in the management of radiation colitis.

Authors:  Jannis Kountouras; Christos Zavos
Journal:  World J Gastroenterol       Date:  2008-12-28       Impact factor: 5.742

Review 3.  Colonography by CT, MRI and PET/CT combined with conventional colonoscopy in colorectal cancer screening and staging.

Authors:  Long Sun; Hua Wu; Yong-Song Guan
Journal:  World J Gastroenterol       Date:  2008-02-14       Impact factor: 5.742

4.  Radiation-induced distal ileal obstruction complicating ileostomy closure.

Authors:  Z Zakaria; D Toomey; J Deasy
Journal:  Tech Coloproctol       Date:  2013-03-20       Impact factor: 3.781

  4 in total

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