Literature DB >> 3631669

Multicenter hypothermia survey.

D F Danzl, R S Pozos, P S Auerbach, S Glazer, W Goetz, E Johnson, J Jui, P Lilja, J A Marx, J Miller.   

Abstract

A multicenter survey evaluated the clinical presentation, treatment, and outcome of accidental hypothermia. Data were collected from 13 emergency departments, with 401 of the 428 cases presenting during a two-year study period. Core temperatures ranged from 35 C to 15.6 C (mean, 30.57 C +/- 3.53) with 272 cases (63.6%) less than or equal to 32.2 C. There were no significant differences by age in presenting temperature, rewarming strategies, or mortality. The first hour rewarming rate was significantly (P less than .05) faster in the population less than or equal to 59 years (1.08 +/- 1.39 C/hr) than in those greater than or equal to 60 years (0.75 +/- 1.16 C/hr). Male core temperatures averaged 30.27 +/- 3.44 C versus female temperatures of 31.1 +/- 3.61 C. There were no clinically significant differences in male (N = 296) versus female (N = 132) profiles. High ethanol levels (315 to 800 mg%) did not affect outcome. Nine of 27 (33%) patients who received CPR initiated in the field survived, versus six of 14 (43%) with CPR begun in the ED. The profile of the CPR versus non-CPR population differed significantly (P less than .05) in location (outdoors), initial temperature (24.8 +/- 3.77 C vs 30.94 +/- 3.12 C), third-hour rewarming rate (2.28 +/- 1.53 C vs 1.17 +/- 1.18 C/hr), and numerous laboratory parameters. Tracheal intubation was performed without incident in 117 cases, of which 97 were less than or equal to 32.2 C. There were 73 fatalities (17.1%). Of these, 84.9% (N = 62) were less than or equal to 32.2 C. Predisposing conditions in this group included "serious" illness (30), systemic infection (28), trauma (15), immersion (ten), frostbite (seven), and overdose (two). The initial pulse, hemoglobin, and first-hour rewarming rate was lower in the deceased population, while the potassium, urea nitrogen, creatinine, and phosphorus were elevated. Excluding treatment combinations, outcome with exclusive use of a single rewarming strategy was passive external rewarming, 14 deaths below 32.2 C, 13 above; active external rewarming, six deaths below 32.2 C, two above; active core rewarming, 38 deaths below 32.2 C, none above. Refinements of the American Heart Association's CPR standards in hypothermia and a Hypothermia Survival Index are proposed.

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Mesh:

Year:  1987        PMID: 3631669     DOI: 10.1016/s0196-0644(87)80757-6

Source DB:  PubMed          Journal:  Ann Emerg Med        ISSN: 0196-0644            Impact factor:   5.721


  27 in total

1.  Acute respiratory distress syndrome associated with accidental hypothermia.

Authors:  T Taniguchi; K Okeie; Y Mizukoshi; K Shibata
Journal:  Intensive Care Med       Date:  2001-04       Impact factor: 17.440

Review 2.  Out of the cold: management of hypothermia and frostbite.

Authors:  Jay Biem; Niels Koehncke; Dale Classen; James Dosman
Journal:  CMAJ       Date:  2003-02-04       Impact factor: 8.262

3.  Accidental hypothermia and death from cold in urban areas.

Authors:  M Tanaka; S Tokudome
Journal:  Int J Biometeorol       Date:  1991-03       Impact factor: 3.787

4.  Thrombin generation and fibrin clot formation under hypothermic conditions: an in vitro evaluation of tissue factor initiated whole blood coagulation.

Authors:  Matthew F Whelihan; Armin Kiankhooy; Kathleen E Brummel-Ziedins
Journal:  J Crit Care       Date:  2013-10-29       Impact factor: 3.425

Review 5.  [Impact of hypothermia on the severely injured patient].

Authors:  P Kobbe; P Lichte; M Wellmann; F Hildebrand; D Nast-Kolb; C Waydhas; R Oberbeck
Journal:  Unfallchirurg       Date:  2009-12       Impact factor: 1.000

6.  Hypothermia deaths in Jefferson County, Alabama.

Authors:  A J Taylor; G McGwin; G G Davis; R M Brissie; T D Holley; L W Rue
Journal:  Inj Prev       Date:  2001-06       Impact factor: 2.399

7.  Hypothermic cardiac arrest in the homeless: what can we do?

Authors:  Fabrizio Sansone; Roberto Flocco; Edoardo Zingarelli; Guglielmo Mario Actis Dato; Giuseppe Punta; Francesco Parisi; Pier Giuseppe Forsennati; Gian Luca Bardi; Iulia Imbastaro; Claudia Chiolero; Adalberto Balossino; Paolo Borin; Viviana Peretto; Stefano del Ponte; Riccardo Casabona
Journal:  J Extra Corpor Technol       Date:  2011-12

8.  Active intravascular rewarming for hypothermia associated with traumatic injury: early experience with a new technique.

Authors:  Edward E Taylor; James P Carroll; Matthew A Lovitt; Laura B Petrey; Paul E Gray; Cyndi J Mastropieri; Michael L Foreman
Journal:  Proc (Bayl Univ Med Cent)       Date:  2008-04

Review 9.  Perioperative management of the bleeding patient.

Authors:  K Ghadimi; J H Levy; I J Welsby
Journal:  Br J Anaesth       Date:  2016-12       Impact factor: 9.166

10.  Severe traumatic head injury in adults: which patients are at risk of early hyperthermia?

Authors:  Arnaud Geffroy; Régis Bronchard; Paul Merckx; Pierre-François Seince; Thierry Faillot; Pierre Albaladejo; Jean Marty
Journal:  Intensive Care Med       Date:  2004-03-30       Impact factor: 17.440

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