Literature DB >> 3630854

Quantitative analysis of intestinal ulceration induced by indomethacin, in rats.

E Ezer.   

Abstract

It has been developed a new simple method for the evaluation of intestinal ulceration induced by indomethacin or other drug in rats. It is well known that the erosion caused by ulcerogenesis leads to the weakening of the strength of the intestinal wall. Simply measuring the tensile strength of intestinal wall, by inflatation, in the experimental animals provides quantitative indices of the severity of ulceration.

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Year:  1987        PMID: 3630854     DOI: 10.1007/BF01974938

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  6 in total

1.  A complementary method for the quantitative evaluation of rat stomach with Shay-ulcer.

Authors:  E Ezer; L Szporny
Journal:  J Pharm Pharmacol       Date:  1975-11       Impact factor: 3.765

2.  A CLINICAL TRIAL OF INDOMETHACIN IN RHEUMATOID ARTHRITIS.

Authors:  A M KATZ; C M PEARSON; J M KENNEDY
Journal:  Clin Pharmacol Ther       Date:  1965 Jan-Feb       Impact factor: 6.875

3.  Jejunal ulcers produced by indomethacin.

Authors:  A Somogyi; K Kovács; H Selye
Journal:  J Pharm Pharmacol       Date:  1969-02       Impact factor: 3.765

4.  Intestinal perforation associated with osmotic slow release indomethacin capsules.

Authors:  T K Day
Journal:  Br Med J (Clin Res Ed)       Date:  1983-12-03

5.  Role of food in gastrointestinal ulceration produced by indomethacin in the rat.

Authors:  H Satoh; P H Guth; M I Grossman
Journal:  Gastroenterology       Date:  1982-07       Impact factor: 22.682

6.  Use of anti-inflammatory drugs by patients admitted with small or large bowel perforations and haemorrhage.

Authors:  M J Langman; L Morgan; A Worrall
Journal:  Br Med J (Clin Res Ed)       Date:  1985-02-02
  6 in total

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