Literature DB >> 3630593

Spinal anaesthesia with hyperbaric tetracaine: effect of age and body mass.

M Tuominen, M Pitkänen, M Doepel, P H Rosenberg.   

Abstract

To discover the influence of age and body mass on spinal analgesia with hyperbaric tetracaine, 60 patients (17-82 years) were administered a subarachnoid injection of 15 mg tetracaine in 3 ml of 5% glucose. The patients were in the lateral position during the injection and in the supine position thereafter. The maximal spread of analgesia (mean T4, range T1-T11) did not correlate with age or body mass. Any variable studied was not significantly different for the different age groups. In 29 patients (48%) the block required supplementation with fentanyl or general anaesthesia (five patients). Tourniquet-induced pain occurred in eight patients (28% of patients with tourniquet). Decreases in systolic arterial blood pressure, greater than 30% of the preanaesthetic value, correlated with the level of analgesia and were more frequent in patients over 50 years (P less than 0.01). Severe hypotension and bradycardia with transient serious changes in QRS-complexes occurred in one patient (analgesia level, T3). In conclusion, 15 mg of hyperbaric tetracaine provided a relatively high sensory spinal blockade without correlating with age or body mass. Supplementation of analgesia during surgery was needed in almost half of the patient material.

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Year:  1987        PMID: 3630593     DOI: 10.1111/j.1399-6576.1987.tb02606.x

Source DB:  PubMed          Journal:  Acta Anaesthesiol Scand        ISSN: 0001-5172            Impact factor:   2.105


  5 in total

1.  The intrathecal spread of hyperbaric dibucaine in adolescents.

Authors:  Y Hirabayashi; R Shimizu
Journal:  J Anesth       Date:  1993-04       Impact factor: 2.078

2.  Comparison of hyperbaric solutions of bupivacaine and tetracaine during continuous spinal anaesthesia.

Authors:  E F Van Gessel; B Miege; A Forster; G Salvaj; M Fathi; Z Gamulin
Journal:  Can J Anaesth       Date:  1992-04       Impact factor: 5.063

Review 3.  Regional anaesthesia in the elderly: a clinical guide.

Authors:  Ban C H Tsui; Alese Wagner; Brendan Finucane
Journal:  Drugs Aging       Date:  2004       Impact factor: 3.923

Review 4.  Clinical pharmacokinetics of epidural and spinal anaesthesia.

Authors:  A G Burm
Journal:  Clin Pharmacokinet       Date:  1989-05       Impact factor: 6.447

Review 5.  Practical Regional Anesthesia Guide for Elderly Patients.

Authors:  Carole Lin; Curtis Darling; Ban C H Tsui
Journal:  Drugs Aging       Date:  2019-03       Impact factor: 3.923

  5 in total

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