Literature DB >> 3627350

'Increased calcium-current' hypothesis of brain aging.

P W Landfield.   

Abstract

Based on evidence that high Mg2+ counteracts age-related declines in synaptic plasticity, and that aged rat hippocampal neurons exhibit prolonged Ca2+-dependent K+ currents, it is proposed that an underlying cause of altered Ca2+ homeostasis during brain aging may be an increased membrane conductance to Ca2+. An apparent Ca2+-mediated inactivation of Ca2+ current, which was recently described in hippocampus, could account for some of the contradictions in the literature.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3627350     DOI： 10.1016/0197-4580(87)90074-1

Source DB:  PubMed          Journal:  Neurobiol Aging        ISSN： 0197-4580            Impact factor:   4.673


  63 in total

1.  Single-cell screening of cytosolic [Ca(2+)] reveals cell-selective action by the Alzheimer's Aβ peptide ion channel.

Authors:  Hopi Lin; Nelson J Arispe
Journal:  Cell Stress Chaperones       Date:  2014-11-01       Impact factor: 3.667

2.  Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses.

Authors:  Wayne Chadwick; Yu Zhou; Sung-Soo Park; Liyun Wang; Nicholas Mitchell; Matthew D Stone; Kevin G Becker; Bronwen Martin; Stuart Maudsley
Journal:  PLoS One       Date:  2010-12-17       Impact factor: 3.240

3.  Novel mechanism of increased Ca2+ release following oxidative stress in neuronal cells involves type 2 inositol-1,4,5-trisphosphate receptors.

Authors:  S Kaja; R S Duncan; S Longoria; J D Hilgenberg; A J Payne; N M Desai; R A Parikh; S L Burroughs; E V Gregg; D L Goad; P Koulen
Journal:  Neuroscience       Date:  2010-11-11       Impact factor: 3.590

Review 4.  The impact of hippocampal lesions on trace-eyeblink conditioning and forebrain-cerebellar interactions.

Authors:  Craig Weiss; John F Disterhoft
Journal:  Behav Neurosci       Date:  2015-08       Impact factor: 1.912

5.  Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons.

Authors:  John C Gant; Kuey-Chu Chen; Christopher M Norris; Inga Kadish; Olivier Thibault; Eric M Blalock; Nada M Porter; Philip W Landfield
Journal:  J Neurosci       Date:  2011-02-02       Impact factor: 6.167

6.  Microarray analyses of laser-captured hippocampus reveal distinct gray and white matter signatures associated with incipient Alzheimer's disease.

Authors:  Eric M Blalock; Heather M Buechel; Jelena Popovic; James W Geddes; Philip W Landfield
Journal:  J Chem Neuroanat       Date:  2011-07-02       Impact factor: 3.052

Review 7.  The dysregulation of intracellular calcium in Alzheimer disease.

Authors:  Charlene Supnet; Ilya Bezprozvanny
Journal:  Cell Calcium       Date:  2010-01-18       Impact factor: 6.817

8.  Aging changes in voltage-gated calcium currents in hippocampal CA1 neurons.

Authors:  L W Campbell; S Y Hao; O Thibault; E M Blalock; P W Landfield
Journal:  J Neurosci       Date:  1996-10-01       Impact factor: 6.167

9.  Store depletion-induced h-channel plasticity rescues a channelopathy linked to Alzheimer's disease.

Authors:  Timothy F Musial; Elizabeth Molina-Campos; Linda A Bean; Natividad Ybarra; Ronen Borenstein; Matthew L Russo; Eric W Buss; Daniel Justus; Krystina M Neuman; Gelique D Ayala; Sheila A Mullen; Yuliya Voskobiynyk; Christopher T Tulisiak; Jasmine A Fels; Nicola J Corbett; Gabriel Carballo; Colette D Kennedy; Jelena Popovic; Josefina Ramos-Franco; Michael Fill; Melissa R Pergande; Jeffrey A Borgia; Grant T Corbett; Kalipada Pahan; Ye Han; Dane M Chetkovich; Robert J Vassar; Richard W Byrne; M Matthew Oh; Travis R Stoub; Stefan Remy; John F Disterhoft; Daniel A Nicholson
Journal:  Neurobiol Learn Mem       Date:  2018-06-12       Impact factor: 2.877

10.  A bout analysis reveals age-related methylmercury neurotoxicity and nimodipine neuroprotection.

Authors:  Andrew Nathanael Shen; Craig Cummings; Derek Pope; Daniel Hoffman; M Christopher Newland
Journal:  Behav Brain Res       Date:  2016-05-16       Impact factor: 3.332
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.