Literature DB >> 3627349

Hypothesis on the regulation of cytosol calcium concentration and the aging brain.

Z S Khachaturian.   

Abstract

This commentary proposes that neurobiology of aging must look beyond the issue of age related changes in calcium concentrations within the cytosol. The more important question is what causes these changes. Studies of structure, function, and dynamics of membranes may begin to give a better clue about underlying mechanisms of these changes.

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Mesh:

Year:  1987        PMID: 3627349     DOI: 10.1016/0197-4580(87)90073-x

Source DB:  PubMed          Journal:  Neurobiol Aging        ISSN: 0197-4580            Impact factor:   4.673


  55 in total

1.  Single-cell screening of cytosolic [Ca(2+)] reveals cell-selective action by the Alzheimer's Aβ peptide ion channel.

Authors:  Hopi Lin; Nelson J Arispe
Journal:  Cell Stress Chaperones       Date:  2014-11-01       Impact factor: 3.667

2.  Regulation of ryanodine receptor-mediated calcium signaling by presenilins.

Authors:  Andrew J Payne; Simon Kaja; Peter Koulen
Journal:  Receptors Clin Investig       Date:  2015

Review 3.  TRPC channels and their implication in neurological diseases.

Authors:  Senthil Selvaraj; Yuyang Sun; Brij B Singh
Journal:  CNS Neurol Disord Drug Targets       Date:  2010-03       Impact factor: 4.388

Review 4.  The case for rejecting the amyloid cascade hypothesis.

Authors:  Karl Herrup
Journal:  Nat Neurosci       Date:  2015-06       Impact factor: 24.884

Review 5.  Astroglial Calcium Signaling in Aging and Alzheimer's Disease.

Authors:  Alexei Verkhratsky
Journal:  Cold Spring Harb Perspect Biol       Date:  2019-07-01       Impact factor: 10.005

Review 6.  Regulation of intrinsic excitability: Roles for learning and memory, aging and Alzheimer's disease, and genetic diversity.

Authors:  Amy R Dunn; Catherine C Kaczorowski
Journal:  Neurobiol Learn Mem       Date:  2019-08-20       Impact factor: 2.877

Review 7.  The dysregulation of intracellular calcium in Alzheimer disease.

Authors:  Charlene Supnet; Ilya Bezprozvanny
Journal:  Cell Calcium       Date:  2010-01-18       Impact factor: 6.817

8.  Mechanisms underlying basal and learning-related intrinsic excitability in a mouse model of Alzheimer's disease.

Authors:  C C Kaczorowski; E Sametsky; S Shah; R Vassar; J F Disterhoft
Journal:  Neurobiol Aging       Date:  2009-10-14       Impact factor: 4.673

Review 9.  Control of intracellular calcium signaling as a neuroprotective strategy.

Authors:  R Scott Duncan; Daryl L Goad; Michael A Grillo; Simon Kaja; Andrew J Payne; Peter Koulen
Journal:  Molecules       Date:  2010-03-03       Impact factor: 4.411

10.  Regional differences in glutaminase activation by phosphate and calcium in rat brain: impairment in aged rats and implications for regional glutaminase isozymes.

Authors:  D R Wallace; R Dawson
Journal:  Neurochem Res       Date:  1993-12       Impact factor: 3.996

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