Literature DB >> 36269692

An update on oral clinical courses among patients with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection: A clinical follow-up (a prospective prevalent cohort) study.

Heron Gezahegn Gebretsadik1.   

Abstract

INTRODUCTION: Contemporary literature has revealed that Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) causes acute sialadenitis and related symptoms, such as discomfort, pain, swelling, and secretory dysfunction in salivary glands. The secretory dysfunction is due to SARS-CoV-2 infection-induced xerostomia and other associated clinical courses such as sore tongue, mucosal ulcer, and gingivitis in the oral cavity. Furthermore, it has been reported that COVID-19 causes the development of other oral manifestations.
MATERIALS AND METHODS: A prospective clinical follow-up (a prevalent cohort) study was conducted to identify the possible oral manifestations of SARS-CoV-2 infection among patients admitted toat the Eka General Hospital COVID-19 treatment center. Furthermore, the study aimed to calculate the prevalence rate of oral clinical courses in the cohorts. The study consisted of two follow-up phases: Hospital and patient-home-based.
RESULTS: A total of 55 patients (36 males and 19 females) met the inclusion criteria and were followed for 7.5 weeks. The 3.5 weeks hospital-based prospective follow-up study documented an 18% (n = 10) prevalence rate of oral clinical courses among the cohorts. Twelve oral symptoms appeared in these ten patients. The manifested oral symptoms were oral mucosal lesions (n = 6), xerostomia (n = 5), and thickening of saliva (n = 1). The oral mucosal lesions per se consisted of aphthous lesions (n = 3), candidiasis (n = 1), geographic tongue (n = 1), and localized gingivitis (n = 1). The four weeks' home-based follow-up study disclosed four newly manifested oral symptoms: hemorrhagic crust, bulla, buccal mucositis, and petechiae. These manifestations appeared among six patients (four males and two females) who had not manifested any oral symptoms during the hospital-based follow-up. Accordingly, the overall prevalence of oral clinical courses among patients presented with SARS-CoV-2 is raised from 18% (n = 10) to 29% (n = 16). Similarly, the number of clinical courses increased from 12 to 16 after four additional weeks of follow-up. DISCUSSION: The study's findings suggest the importance of initiating oral health care for patients with COVID-19. Therefore, multidisciplinary healthcare approaches should be delivered to assure optimal health outcomes. Accordingly, oral health professionals must be a substantial part of the interdisciplinary approach in caring for patients with COVID-19.

Entities:  

Year:  2022        PMID: 36269692      PMCID: PMC9586351          DOI: 10.1371/journal.pone.0275817

Source DB:  PubMed          Journal:  PLoS One        ISSN: 1932-6203            Impact factor:   3.752


  45 in total

1.  Oral Health Implications of SARS-CoV-2/COVID-19: A Systematic Review.

Authors:  Maria Vilar Doceda; Marianna Gavriiloglou; Catherine Petit; Olivier Huck
Journal:  Oral Health Prev Dent       Date:  2022-04-27       Impact factor: 1.256

2.  ACE2 and TMPRSS2 immunolocalization and oral manifestations of COVID-19.

Authors:  Gi Cheol Park; Soo-Young Bang; Hyoun Wook Lee; Kyung Un Choi; Ji Min Kim; Sung-Chan Shin; Yong-Il Cheon; Eui-Suk Sung; Minhyung Lee; Jin-Choon Lee; Hyung-Sik Kim; Byung-Joo Lee
Journal:  Oral Dis       Date:  2022-01-09       Impact factor: 3.511

3.  Oral mucositis in a SARS-CoV-2-infected patient: Secondary or truly associated condition?

Authors:  Saygo Tomo; Glauco Issamu Miyahara; Luciana Estevam Simonato
Journal:  Oral Dis       Date:  2020-08-06       Impact factor: 3.511

Review 4.  Coronavirus Disease 19 (COVID-19): Implications for Clinical Dental Care.

Authors:  Amber Ather; Biraj Patel; Nikita B Ruparel; Anibal Diogenes; Kenneth M Hargreaves
Journal:  J Endod       Date:  2020-04-06       Impact factor: 4.171

Review 5.  COVID-19 from the perspective of dentists: A case report and brief review of more than 170 cases.

Authors:  Reyhaneh Eghbali Zarch; Pegah Hosseinzadeh
Journal:  Dermatol Ther       Date:  2021-01-01       Impact factor: 3.858

6.  TASTE DISORDERS AND XEROSTOMIA ARE HIGHLY PREVALENT IN PATIENTS WITH COVID-19.

Authors:  Satheesh Elangovan
Journal:  J Evid Based Dent Pract       Date:  2021-12-24       Impact factor: 5.267

7.  Necrotizing periodontal disease: Oral manifestation of COVID-19.

Authors:  Jay Patel; Julian Woolley
Journal:  Oral Dis       Date:  2020-06-22       Impact factor: 4.068

Review 8.  Viral infections of oral cavity.

Authors:  Arvind Babu Rajendra Santosh; Keerthi Muddana
Journal:  J Family Med Prim Care       Date:  2020-01-28

9.  Post-extubation dysphagia and dysphonia amongst adults with COVID-19 in the Republic of Ireland: A prospective multi-site observational cohort study.

Authors:  Julie Regan; Margaret Walshe; Sarah Lavan; Eanna Horan; Patricia Gillivan Murphy; Anne Healy; Caoimhe Langan; Karen Malherbe; Breda Flynn Murphy; Maria Cremin; Denise Hilton; Jenni Cavaliere; Alice Whyte
Journal:  Clin Otolaryngol       Date:  2021-07-18       Impact factor: 2.729

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