Yan Wang1, Ingo Fietze2,3, Matthew Salanitro2, Thomas Penzel2. 1. Interdisciplinary Sleep Medicine Center, Charité-Universitätsmedizin Berlin, Luisenstrasse 13, 10117, Berlin, Germany. yan.wang@charite.de. 2. Interdisciplinary Sleep Medicine Center, Charité-Universitätsmedizin Berlin, Luisenstrasse 13, 10117, Berlin, Germany. 3. The Federal State Autonomous Educational Institution of Higher Education, I.M Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Moscow, Russia.
Abstract
PURPOSE: Despite polysomnography being the gold standard method of diagnosing obstructive sleep apnea (OSA), it is time-consuming and has long waiting lists. Alternative methods including questionnaires and portable sleep devices have been developed to increase the speed of diagnosis. However, most questionnaires such as the STOP-BANG questionnaire (SBQ) are limited due to low specificity. This study evaluated the value of SBQ to screen for OSA and compared it with the oxygen desaturation index (ODI) and their combination. METHODS: This retrospective study included patients who completed the SBQ and underwent a night at the sleep lab or home sleep testing. The ODI was extracted from these sleep study reports. The combination of SBQ with ODI and their individual scores were compared with apnea-hypopnea index (AHI) in terms of their accuracy in diagnosing OSA. Sensitivity, specificity, and area under the curve (AUC) for different severities of OSA were calculated and compared. RESULTS: Among 132 patients, SBQ showed a sensitivity of 0.9 and a specificity of 0.3 to screen for OSA. As the severity of OSA increased, the sensitivity increased whilst specificity decreased for both measurements. ODI achieved an increased specificity of 0.8 and could correctly diagnose OSA 86% of the time which was better than SBQ's 60%. For all severities of OSA, ODI alone displayed a larger AUC than SBQ and similar AUC to their combination. CONCLUSION: ODI produced a higher specificity and AUC than SBQ. Furthermore, ODI combined with SBQ failed to increase diagnostic value. Therefore, ODI may be the preferred way to initially screen patients for OSA as an easy-to-use alternative compared to SBQ.
PURPOSE: Despite polysomnography being the gold standard method of diagnosing obstructive sleep apnea (OSA), it is time-consuming and has long waiting lists. Alternative methods including questionnaires and portable sleep devices have been developed to increase the speed of diagnosis. However, most questionnaires such as the STOP-BANG questionnaire (SBQ) are limited due to low specificity. This study evaluated the value of SBQ to screen for OSA and compared it with the oxygen desaturation index (ODI) and their combination. METHODS: This retrospective study included patients who completed the SBQ and underwent a night at the sleep lab or home sleep testing. The ODI was extracted from these sleep study reports. The combination of SBQ with ODI and their individual scores were compared with apnea-hypopnea index (AHI) in terms of their accuracy in diagnosing OSA. Sensitivity, specificity, and area under the curve (AUC) for different severities of OSA were calculated and compared. RESULTS: Among 132 patients, SBQ showed a sensitivity of 0.9 and a specificity of 0.3 to screen for OSA. As the severity of OSA increased, the sensitivity increased whilst specificity decreased for both measurements. ODI achieved an increased specificity of 0.8 and could correctly diagnose OSA 86% of the time which was better than SBQ's 60%. For all severities of OSA, ODI alone displayed a larger AUC than SBQ and similar AUC to their combination. CONCLUSION: ODI produced a higher specificity and AUC than SBQ. Furthermore, ODI combined with SBQ failed to increase diagnostic value. Therefore, ODI may be the preferred way to initially screen patients for OSA as an easy-to-use alternative compared to SBQ.
Authors: O Le Bon; L Staner; G Hoffmann; M Dramaix; I San Sebastian; J R Murphy; M Kentos; I Pelc; P Linkowski Journal: J Psychiatr Res Date: 2001 May-Jun Impact factor: 4.791
Authors: W Ward Flemons; Neil J Douglas; Samuel T Kuna; Daniel O Rodenstein; John Wheatley Journal: Am J Respir Crit Care Med Date: 2004-03-15 Impact factor: 21.405
Authors: Warren R Ruehland; Peter D Rochford; Fergal J O'Donoghue; Robert J Pierce; Parmjit Singh; Andrew T Thornton Journal: Sleep Date: 2009-02 Impact factor: 5.849
Authors: Chamara V Senaratna; Jennifer L Perret; Caroline J Lodge; Adrian J Lowe; Brittany E Campbell; Melanie C Matheson; Garun S Hamilton; Shyamali C Dharmage Journal: Sleep Med Rev Date: 2016-07-18 Impact factor: 11.609
Authors: Christianne C A F M Veugen; Emma M Teunissen; Leontine A S den Otter; Martijn P Kos; Robert J Stokroos; Marcel P Copper Journal: Sleep Breath Date: 2020-10-24 Impact factor: 2.816