Literature DB >> 36268436

Acute recurrent pancreatitis in a child with pancreatic divisum- A case report.

Ojas Thapa1, Sunil Basukala2, Manju Shrestha3, Yugant Khand1, Soumya Pahari1, Sujan Bohara4, Anup Thapa2, Aashish Shah5.   

Abstract

Introduction and importance: In children, acute recurrent pancreatitis is attributed to pancreato-biliary anomalies, hereditary pancreatitis and cystic fibrosis. Pancreatic divisum is a common congenital ductal anomaly that leads to recurrence of pancreatitis. Case presentation: A 13 years old female presented with clinical features of acute recurrent pancreatitis. After ruling out common causes, magnetic resonance cholangiopancreatography was done which showed pancreatic divisum. Her symptoms resolved following duodenum preserving pancreatic head resection. Discussion: Acute recurrent pancreatitis is attributed to raised intrapancreatic dorsal ductal pressure due to ductal anomalies especially pancreatic divisum (PD). It is the embryological failure in the fusion of the dorsal and ventral ductal system. PD is further classified into a classical subtype where there is complete failure of ductal fusion and an incomplete subtype where there is partial fusion of the ductal system. The diagnosis is commonly done through abdominal imaging with secretin enhanced magnetic resonance cholangiopancreatography being the choice of imaging modality. The initial approach is endoscopic intervention unless patients present with signs of pancreatic fibrosis where a duodenum preserving pancreatic head resection can be carried out.
Conclusion: A keen suspicion should be given towards anatomical or structural variants in absence of common etiologies. Early identification and management of pancreatic divisum prevents the recurrence of pancreatitis.
© 2022 The Authors.

Entities:  

Keywords:  Acute recurrent pancreatitis; Case report; MRCP; Pancreatic divisum

Year:  2022        PMID: 36268436      PMCID: PMC9577615          DOI: 10.1016/j.amsu.2022.104642

Source DB:  PubMed          Journal:  Ann Med Surg (Lond)        ISSN: 2049-0801


  17 in total

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4.  Administration of secretin (RG1068) increases the sensitivity of detection of duct abnormalities by magnetic resonance cholangiopancreatography in patients with pancreatitis.

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Journal:  Gastroenterology       Date:  2014-06-04       Impact factor: 22.682

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Authors:  Pier Alberto Testoni
Journal:  World J Gastroenterol       Date:  2014-12-07       Impact factor: 5.742

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Journal:  Can J Gastroenterol       Date:  2003-06       Impact factor: 3.522

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Authors:  T C Simmons; D R Henderson; F Gletten
Journal:  J Natl Med Assoc       Date:  1988-04       Impact factor: 1.798

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