Literature DB >> 3626774

Chiral discrimination in the exchange of alpha-tocopherol stereoisomers between plasma and red blood cells.

S C Cheng, G W Burton, K U Ingold, D O Foster.   

Abstract

The transport of 2R,4'R,8'-alpha-tocopherol and 2S,4'R,8'R-alpha-tocopherol from plasma into rat red blood cell membranes occurs with essentially no chiral discrimination. The previously demonstrated (10) preference of red blood cell membranes favoring 2R,4'R,8'R-alpha-tocopherol over the 2S,4'R,8'R stereoisomer is shown to be due to better retention of the former compound, i.e., to preferential retention of natural vitamin E.

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Year:  1987        PMID: 3626774     DOI: 10.1007/BF02540361

Source DB:  PubMed          Journal:  Lipids        ISSN: 0024-4201            Impact factor:   1.880


  16 in total

1.  BIOPOTENCY OF L-ALPHA-TOCOPHERYL ACETATE FOR THE RAT.

Authors:  L A WITTING; M K HORWITT
Journal:  Proc Soc Exp Biol Med       Date:  1964-07

2.  THE RELATIVE ANTI-MUSCULAR DYSTROPHY ACTIVITY OF THE D- AND L-EPIMERS OF ALPHA-TOCOPHEROL AND OF OTHER TOCOPHEROLS IN THE CHICK.

Authors:  M L SCOTT; I D DESAI
Journal:  J Nutr       Date:  1964-05       Impact factor: 4.798

3.  Blood alpha tocopherol: erythrocyte and plasma relationships in vitro and in vivo.

Authors:  R K Poukka; J G Bieri
Journal:  Lipids       Date:  1970-09       Impact factor: 1.880

4.  A mild, rapid, and efficient method of lipid extraction for use in determining vitamin E/lipid ratios.

Authors:  G W Burton; A Webb; K U Ingold
Journal:  Lipids       Date:  1985-01       Impact factor: 1.880

5.  Specific binding sites for D-alpha-tocopherol on human erythrocytes.

Authors:  A E Kitabchi; J Wimalasena
Journal:  Biochim Biophys Acta       Date:  1982-01-22

6.  Estimation of the location of natural alpha-tocopherol in lipid bilayers by 13C-NMR spectroscopy.

Authors:  B Perly; I C Smith; L Hughes; G W Burton; K U Ingold
Journal:  Biochim Biophys Acta       Date:  1985-09-25

7.  Biopotency of alpha-tocopherols as determined by curative myopathy bioassay in the rat.

Authors:  L J Machlin; E Gabriel; M Brin
Journal:  J Nutr       Date:  1982-07       Impact factor: 4.798

8.  Biopotencies in rats of several forms of alpha-tocopherol.

Authors:  S R Ames
Journal:  J Nutr       Date:  1979-12       Impact factor: 4.798

9.  Determination of alpha-tocopherol in erythrocytes by gas-liquid chromatography.

Authors:  J G Bieri; R K Poukka; E L Prival
Journal:  J Lipid Res       Date:  1970-03       Impact factor: 5.922

10.  Biokinetics of and discrimination between dietary RRR- and SRR-alpha-tocopherols in the male rat.

Authors:  K U Ingold; G W Burton; D O Foster; L Hughes; D A Lindsay; A Webb
Journal:  Lipids       Date:  1987-03       Impact factor: 1.880

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  2 in total

1.  Absorption and transport of deuterium-substituted 2R,4'R,8'R-alpha-tocopherol in human lipoproteins.

Authors:  M G Traber; K U Ingold; G W Burton; H J Kayden
Journal:  Lipids       Date:  1988-08       Impact factor: 1.880

2.  Comparison of free alpha-tocopherol and alpha-tocopheryl acetate as sources of vitamin E in rats and humans.

Authors:  G W Burton; K U Ingold; D O Foster; S C Cheng; A Webb; L Hughes; E Lusztyk
Journal:  Lipids       Date:  1988-09       Impact factor: 1.880

  2 in total

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