Literature DB >> 36267129

Novel SMARCA Degraders for Treating Cancer.

Ram W Sabnis1.   

Abstract

Provided herein are novel compounds as SMARCA degraders, pharmaceutical compositions, use of such compounds in treating cancer, and processes for preparing such compounds. Published 2022 by American Chemical Society.

Entities:  

Year:  2022        PMID： 36267129      PMCID： PMC9578032          DOI： 10.1021/acsmedchemlett.2c00379

Source DB:  PubMed          Journal:  ACS Med Chem Lett        ISSN： 1948-5875            Impact factor:   4.632


  6 in total

Review 1.  Transforming targeted cancer therapy with PROTACs: A forward-looking perspective.

Authors:  William Farnaby; Manfred Koegl; Darryl B McConnell; Alessio Ciulli
Journal:  Curr Opin Pharmacol       Date:  2021-03-30       Impact factor: 5.547

Review 2.  Reviewing the toolbox for degrader development in oncology.

Authors:  Joel O Cresser-Brown; Graham P Marsh; Hannah J Maple
Journal:  Curr Opin Pharmacol       Date:  2021-05-28       Impact factor: 5.547

Review 3.  Advances and perspectives of proteolysis targeting chimeras (PROTACs) in drug discovery.

Authors:  Jia-Yue Xi; Ru-Yue Zhang; Ke Chen; Lin Yao; Mu-Qiong Li; Ru Jiang; Xiao-Ye Li; Li Fan
Journal:  Bioorg Chem       Date:  2022-05-05       Impact factor: 5.275

Review 4.  Targeting epigenetic modulators using PROTAC degraders: Current status and future perspective.

Authors:  Thomas Webb; Conner Craigon; Alessio Ciulli
Journal:  Bioorg Med Chem Lett       Date:  2022-03-04       Impact factor: 2.823

Review 5.  Proteolysis-targeting chimeras: A promising technique in cancer therapy for gaining insights into tumor development.

Authors:  Moyang Lv; Weichao Hu; Shengwei Zhang; Lijiao He; Changjiang Hu; Shiming Yang
Journal:  Cancer Lett       Date:  2022-04-30       Impact factor: 9.756

Review 6.  Exploiting epigenetic dependencies in ovarian cancer therapy.

Authors:  Aisling Y Coughlan; Giuseppe Testa
Journal:  Int J Cancer       Date:  2021-08-06       Impact factor: 7.316
  6 in total

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