Sreenu Thupakula1, Shiva Shankar Reddy Nimmala1, Haritha Ravula2, Sudhakar Chekuri3, Raju Padiya4. 1. Department of Biochemistry, Osmania University, Amberpet, Hyderabad, Telangana, 500007, India. 2. Department of Plant Sciences, University of Hyderabad, Gopanpalle, Hyderabad, Telangana, 500019, India. 3. Department of Genetics, Osmania University, Amberpet, Hyderabad, Telangana, 500007, India. 4. Department of Biochemistry, Osmania University, Amberpet, Hyderabad, Telangana, 500007, India. rajupadiya@gmail.com.
Abstract
BACKGROUND: The prevalence of cardiovascular disease (CVD) has been continuously increasing, and this trend is projected to continue. CVD is rapidly becoming a significant public health issue. Every year there is a spike in hospital cases of CVD, a critical health concern in lower- and middle-income countries. Based on identification of novel biomarkers, it would be necessary to study and evaluate the diagnostic requirements or CVD to expedite early detection. MAIN BODY: The literature review was written using a wide range of sources, such as well-known medical journals, electronic databases, manuscripts, texts, and other writings from the university library. After that, we analysed the specific markers of CVD and compiled a systematic review. A growing body of clinical research aims to identify people who are at risk for cardiovascular disease by looking for biomolecules. A small number of biomarkers have been shown to be useful and reliable in medicine. Biomarkers can be used for a variety of clinical applications, such as predicting heart disease risk, diagnosing disease, or predicting outcomes. As a result of the ability for a single molecule to act as a biomarker, its usefulness in medicine is expected to increase significantly. CONCLUSIONS: Based on assessing the current trends in the application of CVD markers, we discussed and described the requirements for the application of CVD biomarkers in coronary heart disease, cerebrovascular disease, rheumatic heart disease, and other cardiovascular illnesses. Furthermore, the current review focuses on biomarkers for CVD and the procedures that should be considered to establish the comprehensive nature of the expression of biomarkers for cardiovascular illness.
BACKGROUND: The prevalence of cardiovascular disease (CVD) has been continuously increasing, and this trend is projected to continue. CVD is rapidly becoming a significant public health issue. Every year there is a spike in hospital cases of CVD, a critical health concern in lower- and middle-income countries. Based on identification of novel biomarkers, it would be necessary to study and evaluate the diagnostic requirements or CVD to expedite early detection. MAIN BODY: The literature review was written using a wide range of sources, such as well-known medical journals, electronic databases, manuscripts, texts, and other writings from the university library. After that, we analysed the specific markers of CVD and compiled a systematic review. A growing body of clinical research aims to identify people who are at risk for cardiovascular disease by looking for biomolecules. A small number of biomarkers have been shown to be useful and reliable in medicine. Biomarkers can be used for a variety of clinical applications, such as predicting heart disease risk, diagnosing disease, or predicting outcomes. As a result of the ability for a single molecule to act as a biomarker, its usefulness in medicine is expected to increase significantly. CONCLUSIONS: Based on assessing the current trends in the application of CVD markers, we discussed and described the requirements for the application of CVD biomarkers in coronary heart disease, cerebrovascular disease, rheumatic heart disease, and other cardiovascular illnesses. Furthermore, the current review focuses on biomarkers for CVD and the procedures that should be considered to establish the comprehensive nature of the expression of biomarkers for cardiovascular illness.
Authors: Hana Thomas; Jamie Diamond; Adrianna Vieco; Shaoli Chaudhuri; Eliezer Shinnar; Sara Cromer; Pablo Perel; George A Mensah; Jagat Narula; Catherine O Johnson; Gregory A Roth; Andrew E Moran Journal: Glob Heart Date: 2018-10-06
Authors: Fred S Apple; Alan H B Wu; Johannes Mair; Jan Ravkilde; Mauro Panteghini; Jillian Tate; Franca Pagani; Robert H Christenson; Martin Mockel; Oliver Danne; Allan S Jaffe Journal: Clin Chem Date: 2005-03-17 Impact factor: 8.327
Authors: Gregory G Schwartz; P Gabriel Steg; Michael Szarek; Deepak L Bhatt; Vera A Bittner; Rafael Diaz; Jay M Edelberg; Shaun G Goodman; Corinne Hanotin; Robert A Harrington; J Wouter Jukema; Guillaume Lecorps; Kenneth W Mahaffey; Angèle Moryusef; Robert Pordy; Kirby Quintero; Matthew T Roe; William J Sasiela; Jean-François Tamby; Pierluigi Tricoci; Harvey D White; Andreas M Zeiher Journal: N Engl J Med Date: 2018-11-07 Impact factor: 91.245