Literature DB >> 36264329

Comparative study between topical steroid alone versus combined fractional Erbium:YAG laser with topical steroid in treatment of alopecia areata.

Hesham Ali Shokeir1, Anas Yousry2, Shady Mahmoud Attia Ibrahim3.   

Abstract

AA is a common autoimmune skin disease that causes hair loss on the scalp and sometimes other areas of the body. New therapy approaches for alopecia areata are emerging, with the goal of improving clinical outcomes. In this study, the effects of topical steroids against fractional Er:YAG laser followed by topical steroids in the treatment of alopecia areata will be compared. A total of 30 participants with alopecia areata were included in the study. Each patient's lesions were treated with one of two methods: topical clobetasol propionate or fractional Er:YAG laser followed by topical clobetasol propionate. SALT score, patient satisfaction, and dermoscopic imaging were used to evaluate therapeutic response. Both treatment modalities showed a significant clinical improvement in alopecia areata with a statistically significant reduction in the SALT score. The SALT score was more evident in the laser-steroid group. On comparing the dermoscopy findings in both treated areas before and after treatment, a significant reduction was found regarding all dermoscopic findings of alopecia areata in both modalities. Combining fractional Er:YAG laser with topical steroids is found to be a safe treatment modality and more effective than topical steroids in alopecia areata.
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.

Entities:  

Keywords:  Alopecia areata; Clobetasol propionate; Fractional Er:YAG laser

Year:  2022        PMID: 36264329     DOI: 10.1007/s00403-022-02417-0

Source DB:  PubMed          Journal:  Arch Dermatol Res        ISSN: 0340-3696            Impact factor:   3.033


  3 in total

1.  Treatment of alopecia areata with fractional photothermolysis laser.

Authors:  Kwang Ho Yoo; Myeung Nam Kim; Beom Joon Kim; Chan Woong Kim
Journal:  Int J Dermatol       Date:  2009-07-13       Impact factor: 2.736

Review 2.  Topical Corticosteroids: Choice and Application.

Authors:  Stephen K Stacey; Mark McEleney
Journal:  Am Fam Physician       Date:  2021-03-15       Impact factor: 3.292

3.  Erbium: YAG laser (2,940 nm) treatment stimulates hair growth through upregulating Wnt 10b and β-catenin expression in C57BL/6 mice.

Authors:  Jin Ke; Huiwen Guan; Shan Li; Li Xu; Li Zhang; Yuehua Yan
Journal:  Int J Clin Exp Med       Date:  2015-11-15
  3 in total

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