| Literature DB >> 36262980 |
Wenchao Gu1, Xiwen Gao2, Linxun Wang1, Guoping Deng1, Jiaru Huang1, Junxia Yang1, Yuan Liu1, Qun Liu3, Hongyang Sang4.
Abstract
Lung cancer in its occurrence and development of different stages exist different biological behavior changes. This paper studies the expression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 in benign and malignant lung lesions and its early diagnosis value of nonsmall-cell lung cancer (NSCLC), aiming to provide reference for the early diagnosis and therapy of NSCLC. Some lung surgery specimens are selected from January 2021 to March 2022. All cases received no radiotherapy and chemotherapy before surgery, including 90 sufferers with benign lung lesions as the contrast set. hnRNP A2/B1 expressions are measured for comparison. The experimental results show that for lung cancer sufferers, the positive expression of hnRNP A2/B1 in their malignant lesion tissue is notoriously higher than that in their benign lesion tissue, and hnRNP A2/B1 is differently expressed in different differentiation and in different stages.Entities:
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Year: 2022 PMID： 36262980 PMCID： PMC9556203 DOI： 10.1155/2022/5687245
Source DB: PubMed Journal: Contrast Media Mol Imaging ISSN： 1555-4309 Impact factor: 3.009