Literature DB >> 36262911

A Rare Case of Idiopathic Systemic Capillary Leak Syndrome.

Shelina Malla1, Tushar Pawar2, Biswaraj Tharu3, Sijan Basnet1, Andrew C Rettew1, Daniel A Forman1.   

Abstract

Idiopathic systemic capillary leak syndrome (SCLS) is characterized by an increased capillary hyperpermeability with subsequent hemoconcentration, hypoproteinemia, and hypovolemia. Patients present with diffuse swelling, weight gain, low blood pressure, and shock. We present our case of idiopathic SCLS in a 50-year-old man presenting with prodromal flu-like illness associated with shock that was complicated by compartment syndrome requiring four limb fasciotomies, disseminated intravascular coagulation, acute kidney injury requiring dialysis, and cardiac arrest.
© 2022 Greater Baltimore Medical Center.

Entities:  

Keywords:  Capillary hyperpermeability; Clarkson’s disease; Hemoconcentration; Polycythemia; Systemic capillary leak syndrome

Year:  2022        PMID: 36262911      PMCID: PMC9533808          DOI: 10.55729/2000-9666.1083

Source DB:  PubMed          Journal:  J Community Hosp Intern Med Perspect        ISSN: 2000-9666


  6 in total

1.  Cyclical edema and shock due to increased capillary permeability.

Authors:  B CLARKSON; D THOMPSON; M HORWITH; E H LUCKEY
Journal:  Am J Med       Date:  1960-08       Impact factor: 4.965

Review 2.  Narrative review: the systemic capillary leak syndrome.

Authors:  Kirk M Druey; Philip R Greipp
Journal:  Ann Intern Med       Date:  2010-07-20       Impact factor: 25.391

3.  Clinical Presentation, Management, and Prognostic Factors of Idiopathic Systemic Capillary Leak Syndrome: A Systematic Review.

Authors:  Tae Seong Eo; Kyung Ju Chun; Su Jung Hong; Ji Young Kim; I Re Lee; Keum Hwa Lee; Michael Eisenhut; Andreas Kronbichler; Jae Il Shin
Journal:  J Allergy Clin Immunol Pract       Date:  2017-09-19

Review 4.  Systemic capillary leak syndrome.

Authors:  Shotetsu Kawabe; Takako Saeki; Hajime Yamazaki; Masaaki Nagai; Ryuji Aoyagi; Shoji Miyamura
Journal:  Intern Med       Date:  2002-03       Impact factor: 1.271

5.  Idiopathic systemic capillary leak syndrome (Clarkson's disease): the Mayo clinic experience.

Authors:  Prashant Kapoor; Patricia T Greipp; Eric W Schaefer; Sumithra J Mandrekar; Arif H Kamal; Natalia C Gonzalez-Paz; Shaji Kumar; Philip R Greipp
Journal:  Mayo Clin Proc       Date:  2010-07-15       Impact factor: 7.616

6.  Idiopathic systemic capillary leak syndrome (Clarkson syndrome) in childhood: systematic literature review.

Authors:  Marie-Ange Bozzini; Gregorio P Milani; Mario G Bianchetti; Emilio F Fossali; Sebastiano A G Lava
Journal:  Eur J Pediatr       Date:  2018-06-23       Impact factor: 3.183

  6 in total

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