Literature DB >> 36262898

A Case of Pleural Tuberculosis vs Latent Tuberculosis Reactivation as a Result of COVID-19 Infection and Treatment.

Wesley Tang1, Lex Leonhardt1, Aamir Pervez1, Satish Sarvepalli2.   

Abstract

The reactivation of latent tuberculosis occurs when a patient living with Mycobacterium tuberculosis enters a state where the immune system is suppressed. Since early 2021, the standard of care has been to provide corticosteroids in patients with COVID-19 infection in hospitalized patients receiving supplemental oxygen or mechanical ventilation. The immunomodulatory effects of corticosteroids are potentially detrimental for patients with latent vs active tuberculosis, with concomitant SARS-CoV2 infection. We present one of the first few cases in the literature detailing a case of reactivation of latent tuberculosis vs. pleural tuberculosis as a consequence of COVID-19, and who underwent subsequent corticosteroid treatment.
© 2022 Greater Baltimore Medical Center.

Entities:  

Keywords:  COVID-19 infection; Corticosteroids; Immunosuppression; Latent tuberculosis; Pleural tuberculosis; Tuberculosis reactivation

Year:  2022        PMID： 36262898      PMCID： PMC9533800          DOI： 10.55729/2000-9666.1078

Source DB:  PubMed          Journal:  J Community Hosp Intern Med Perspect        ISSN： 2000-9666


  5 in total

Review 1.  Latent Mycobacterium tuberculosis infection.

Authors:  Haileyesus Getahun; Alberto Matteelli; Richard E Chaisson; Mario Raviglione
Journal:  N Engl J Med       Date:  2015-05-28       Impact factor: 91.245

Review 2.  The Global Burden of Latent Tuberculosis Infection: A Re-estimation Using Mathematical Modelling.

Authors:  Rein M G J Houben; Peter J Dodd
Journal:  PLoS Med       Date:  2016-10-25       Impact factor: 11.069

3.  COVID-19 in a patient with active tuberculosis: A rare case-report.

Authors:  Fahad Faqihi; Abdulrahman Alharthy; AlFateh Noor; Ahmed Balshi; Abdullah Balhamar; Dimitrios Karakitsos
Journal:  Respir Med Case Rep       Date:  2020-07-04

4.  COVID-19 promoting the development of active tuberculosis in a patient with latent tuberculosis infection: A case report.

Authors:  Mohammed Khayat; Hanan Fan; Yusuf Vali
Journal:  Respir Med Case Rep       Date:  2021-01-20

5.  Dexamethasone in Hospitalized Patients with Covid-19.

Authors:  Peter Horby; Wei Shen Lim; Jonathan R Emberson; Marion Mafham; Jennifer L Bell; Louise Linsell; Natalie Staplin; Christopher Brightling; Andrew Ustianowski; Einas Elmahi; Benjamin Prudon; Christopher Green; Timothy Felton; David Chadwick; Kanchan Rege; Christopher Fegan; Lucy C Chappell; Saul N Faust; Thomas Jaki; Katie Jeffery; Alan Montgomery; Kathryn Rowan; Edmund Juszczak; J Kenneth Baillie; Richard Haynes; Martin J Landray
Journal:  N Engl J Med       Date:  2020-07-17       Impact factor: 91.245
  5 in total

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