Feng-Xi Meng1,2,3, Han Yue1,2,3, Yi-Qun Yuan1,2,3, Rui Zhang1,2,3, Yi-Fei Yuan1,2,3, Ying-Wen Bi4, Jiang Qian1,2,3. 1. Department of Ophthalmology, Eye & ENT Hospital of Fudan University, Shanghai 200031, China. 2. Laboratory of Myopia, Chinese Academy of Medical Sciences, Shanghai 200031, China. 3. NHC Key Laboratory of Myopia, Fudan University, Shanghai 200031, China. 4. Department of Pathology, Eye & ENT Hospital of Fudan University, Shanghai 200031, China.
Abstract
AIM: To study the clinical and pathological characteristics of the lacrimal sac lymphoma, which is rare but it is the major type of non-epithelial malignant tumor in the lacrimal sac region. METHODS: Sixty-four cases of malignant lacrimal sac tumors in our hospital from 1986 to 2020 were retrospectively reviewed. Eight cases of lacrimal sac lymphoma were carefully reviewed. RESULTS: There were five mucosal-associated lymphoid tissue (MALT) lymphomas, one diffused large B-cell lymphoma, one NK/T cell lymphoma, and one mantle cell lymphoma. All eight patients represented symptoms of epiphora with swelling in the lacrimal sac for a certain period of time and showed no signs of systemic involvement at the first time of clinical visits. They had received either chemotherapy or radiotherapy after surgery. Long-term follow-up (from 11 to 220mo) showed that, except one patient with MALT lymphoma died for unknown reasons at 104mo after surgery, the other 7 patients were all alive with no signs of local recurrence, neither in other organs. CONCLUSION: Non-epithelial malignant tumors of the lacrimal sac are rare and lymphoma is the major subtype. International Journal of Ophthalmology Press.
AIM: To study the clinical and pathological characteristics of the lacrimal sac lymphoma, which is rare but it is the major type of non-epithelial malignant tumor in the lacrimal sac region. METHODS: Sixty-four cases of malignant lacrimal sac tumors in our hospital from 1986 to 2020 were retrospectively reviewed. Eight cases of lacrimal sac lymphoma were carefully reviewed. RESULTS: There were five mucosal-associated lymphoid tissue (MALT) lymphomas, one diffused large B-cell lymphoma, one NK/T cell lymphoma, and one mantle cell lymphoma. All eight patients represented symptoms of epiphora with swelling in the lacrimal sac for a certain period of time and showed no signs of systemic involvement at the first time of clinical visits. They had received either chemotherapy or radiotherapy after surgery. Long-term follow-up (from 11 to 220mo) showed that, except one patient with MALT lymphoma died for unknown reasons at 104mo after surgery, the other 7 patients were all alive with no signs of local recurrence, neither in other organs. CONCLUSION: Non-epithelial malignant tumors of the lacrimal sac are rare and lymphoma is the major subtype. International Journal of Ophthalmology Press.
Authors: L D Sjö; E Ralfkiaer; B R Juhl; J U Prause; T Kivelä; C Auw-Haedrich; F Bacin; M Carrera; S E Coupland; B Delbosc; N Ducrey; B Kantelip; J L Kemeny; P Meyer; N C Sjö; S Heegaard Journal: Br J Ophthalmol Date: 2006-05-03 Impact factor: 4.638
Authors: Chee-Chew Yip; George B Bartley; Thomas M Habermann; James A Garrity Journal: Ophthalmic Plast Reconstr Surg Date: 2002-07 Impact factor: 1.746