Literature DB >> 36262779

Evaluation of Different Methods for the Detection of Anti- Thyroglobulin Autoantibody: Prevalence of Anti-Thyroglobulin Autoantibody and Anti-Microsomal Autoantibody in Thyroid Cancer Patients.

Chandrakala Gholve1, Archana Damle1, Savita Kulkarni1, Sharmila Banerjee1, Mgr Rajan1.   

Abstract

Four anti-thyroglobulin autoantibodies (TgAb) assays were evaluated for their reference interval, method agreement, concordance etc. Prevalence of TgAb and anti-thyroid peroxidase was studied in differentiated thyroid cancer (DTC) and control. Reference intervals for TgAb assays varied from method to method due to varied assay designs. For TgAb correlation coefficients ranged from 0.74 to 0.99 whereas concordance ranged from 81 to 96.1%. Prevalence of thyroid antibodies mainly TgAb was increased in DTC primarily in females. Use of sensitive immunoassays is recommended for thyroid autoantibody measurement. Diagnosis and follow-up are difficult in DTC with coexisting thyroid autoimmunity. Hence, careful monitoring with regular surveillance is suggested.
© The Author(s), under exclusive licence to Association of Clinical Biochemists of India 2021.

Entities:  

Keywords:  Differentiated Thyroid Cancer (DTC); Prevalence; Reference interval; Thyroglobulin autoantibodies (TgAb); Thyroid peroxidase

Year:  2021        PMID： 36262779      PMCID： PMC9573838          DOI： 10.1007/s12291-021-01005-9

Source DB:  PubMed          Journal:  Indian J Clin Biochem        ISSN： 0970-1915


  17 in total

1.  Can we measure serum thyroglobulin?

Authors:  P M Clark; G Beckett
Journal:  Ann Clin Biochem       Date:  2002-05       Impact factor: 2.057

2.  Laboratory medicine practice guidelines. Laboratory support for the diagnosis and monitoring of thyroid disease.

Authors:  Zubair Baloch; Pierre Carayon; Bernard Conte-Devolx; Laurence M Demers; Ulla Feldt-Rasmussen; Jean-François Henry; Virginia A LiVosli; Patricia Niccoli-Sire; Rhys John; Jean Ruf; Peter P A Smyth; Carole A Spencer; Jan R Stockigt
Journal:  Thyroid       Date:  2003-01       Impact factor: 6.568

3.  Performance characteristics of 5 automated thyroglobulin autoantibody and thyroid peroxidase autoantibody assays.

Authors:  Sonia L La'ulu; Patricia R Slev; William L Roberts
Journal:  Clin Chim Acta       Date:  2006-07-25       Impact factor: 3.786

4.  In-House Solid-Phase Radioassay for the Detection of Anti-thyroglobulin Autoantibodies in Patients with Differentiated Thyroid Cancer.

Authors:  Chandrakala Gholve; J Kumarasamy; Savita Kulkarni; M G R Rajan
Journal:  Indian J Clin Biochem       Date:  2016-05-12

5.  Definition of reference limits for autoantibodies to thyroid peroxidase and thyroglobulin in a large population of outpatients using an indirect method based on current data.

Authors:  Renato Tozzoli; Davide Giavarina; Danilo Villalta; Giuliano Soffiati; Nicola Bizzaro
Journal:  Arch Pathol Lab Med       Date:  2008-12       Impact factor: 5.534

6.  Significance of antithyroglobulin autoantibodies in differentiated thyroid carcinoma.

Authors:  A Kumar; D H Shah; U Shrihari; S R Dandekar; U Vijayan; S M Sharma
Journal:  Thyroid       Date:  1994       Impact factor: 6.568

7.  Comparison of Serum Thyroglobulin Levels in Differentiated Thyroid Cancer Patients Using In-House Developed Radioimmunoassay and Immunoradiometric Procedures.

Authors:  Chandrakala Gholve; J Kumarasamy; Archana Damle; Savita Kulkarni; Meera Venkatesh; Sharmila Banerjee; M G R Rajan
Journal:  Indian J Clin Biochem       Date:  2018-06-18

Review 8.  Thyroglobulin in differentiated thyroid cancer.

Authors:  Carol Evans; Sarah Tennant; Petros Perros
Journal:  Clin Chim Acta       Date:  2014-10-29       Impact factor: 3.786

9.  Change of serum antithyroglobulin antibody levels is useful for prediction of clinical recurrence in thyroglobulin-negative patients with differentiated thyroid carcinoma.

Authors:  Won Gu Kim; Jong Ho Yoon; Won Bae Kim; Tae Yong Kim; Eui Young Kim; Jung Min Kim; Jin-Sook Ryu; Gyungyub Gong; Suck Joon Hong; Young Kee Shong
Journal:  J Clin Endocrinol Metab       Date:  2008-09-23       Impact factor: 5.958

Review 10.  Analytical and clinical performance goals for testing autoantibodies to thyroperoxidase, thyroglobulin, and thyrotropin receptor.

Authors:  U Feldt-Rasmussen
Journal:  Clin Chem       Date:  1996-01       Impact factor: 8.327
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