| Literature DB >> 36261587 |
Bernhard Wernly1,2, Hans Flaatten3,4, Michael Beil5, Jesper Fjølner6, Raphael Romano Bruno7, Antonio Artigas8, Bernardo Bollen Pinto9, Joerg C Schefold10, Malte Kelm7, Sviri Sigal5, Peter Vernon van Heerden11, Wojciech Szczeklik12, Muhammed Elhadi13, Michael Joannidis14, Richard Rezar15, Sandra Oeyen16, Georg Wolff7, Brian Marsh17, Finn H Andersen18,19, Rui Moreno20,21,22, Sarah Wernly2, Susannah Leaver23, Ariane Boumendil24, Dylan W De Lange25, Bertrand Guidet24, Stefan Perings7, Christian Jung26.
Abstract
In Europe, tax-based healthcare systems (THS) and social health insurance systems (SHI) coexist. We examined differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in intensive care units in a THS or SHI. Retrospective cohort study. 2406 (THS n = 886; SHI n = 1520) critically ill ≥ 70 years patients in 129 ICUs. Generalized estimation equations with robust standard errors were chosen to create population average adjusted odds ratios (aOR). Data were adjusted for patient-specific variables, organ support and health economic data. The primary outcome was 30-day-mortality. Numerical differences between SHI and THS in SOFA scores (6 ± 3 vs. 5 ± 3; p = 0.002) were observed, but clinical frailty scores were similar (> 4; 17% vs. 14%; p = 0.09). Higher rates of renal replacement therapy (18% vs. 11%; p < 0.001) were found in SHI (aOR 0.61 95%CI 0.40-0.92; p = 0.02). No differences regarding intubation rates (68% vs. 70%; p = 0.33), vasopressor use (67% vs. 67%; p = 0.90) and 30-day-mortality rates (47% vs. 50%; p = 0.16) were found. Mortality remained similar between both systems after multivariable adjustment and sensitivity analyses. The retrospective character of this study. Baseline risk and mortality rates were similar between SHI and THS. The type of health care system does not appear to have played a role in the intensive care treatment of critically ill patients ≥ 70 years with COVID-19 in Europe.Entities:
Mesh:
Year: 2022 PMID: 36261587 PMCID: PMC9580441 DOI: 10.1038/s41598-022-21580-y
Source DB: PubMed Journal: Sci Rep ISSN: 2045-2322 Impact factor: 4.996