Classification of breast cancer histology images using MSMV-PFENet.

Deep learning has been used extensively in histopathological image classification, but people in this field are still exploring new neural network architectures for more effective and efficient cancer diagnosis. Here, we propose multi-scale, multi-view progressive feature encoding network (MSMV-PFENet) for effective classification. With respect to the density of cell nuclei, we selected the regions potentially related to carcinogenesis at multiple scales from each view. The progressive feature encoding network then extracted the global and local features from these regions. A bidirectional long short-term memory analyzed the encoding vectors to get a category score, and finally the majority voting method integrated different views to classify the histopathological images. We tested our method on the breast cancer histology dataset from the ICIAR 2018 grand challenge. The proposed MSMV-PFENet achieved 93.0[Formula: see text] and 94.8[Formula: see text] accuracies at the patch and image levels, respectively. This method can potentially benefit the clinical cancer diagnosis.