Literature DB >> 36259129

A rare case of pancreatic macrocystic serous cystadenoma in an adolescent: a case report and literature review.

Yu-Jui Chang1, Hung-Chang Lee2,3, Chun-Yan Yeung2,3,4, Wai-Tao Chen2,3, Chuen-Bin Jiang2,3.   

Abstract

While serous cystadenomas of the pancreas usually consist of small cysts, one rare variant has been reported to be composed of macrocysts. Herein, we present the case of the youngest patient with macrocystic serous cystadenoma (MSC) to be reported in the literature. The patient was a 17-year-old girl who presented with the major symptoms of a palpable abdominal mass accompanied by epigastric pain and vomiting for several months. A potential malignancy could not be excluded on the basis of imaging studies, which showed a large macrocystic pancreatic tumor that was 7 cm in diameter. Owing to the patient's symptoms, after diagnosing the mass as a pancreatic cystic tumor with potential malignancy and large tumor size, surgical intervention was arranged. Pathological analysis of the biopsy sample suggested MSC. By reviewing the literature, we found several unique characters of MSCs that cause them to be frequently misdiagnosed as potential malignancies. Additionally, the age of MSC occurrence was found to be lower than of general serous cystadenomas. The potential of MSC should be kept in mind by clinicians when diagnosing young people with pancreatic macrocystic lesions.

Entities:  

Keywords:  Pancreatic neoplasm; adolescent; case report; macrocystic lesion; mucinous cystic neoplasm; serous cystadenoma

Mesh:

Year:  2022        PMID: 36259129      PMCID: PMC9583217          DOI: 10.1177/03000605221129102

Source DB:  PubMed          Journal:  J Int Med Res        ISSN: 0300-0605            Impact factor:   1.573


  27 in total

1.  Macrocystic serous cystadenoma of the pancreas: a morphologic variant differing from microcystic adenoma.

Authors:  K Lewandrowski; A Warshaw; C Compton
Journal:  Hum Pathol       Date:  1992-08       Impact factor: 3.466

2.  Serous microcystic adenoma (glycogen-rich cystadenoma) of the pancreas: study of 11 cases showing clinicopathological and immunohistochemical correlations.

Authors:  Yumiko Yasuhara; Noriko Sakaida; Yoshiko Uemura; Hideto Senzaki; Nobuaki Shikata; Airo Tsubura
Journal:  Pathol Int       Date:  2002-04       Impact factor: 2.534

3.  Obstructive Jaundice as a Complication of Macrocystic Serous Cystadenoma of the Pancreas.

Authors:  Hendra Koncoro; I Komang W D Putra; I Dewa N Wibawa
Journal:  Acta Med Indones       Date:  2016-04

Review 4.  Serous Neoplasms of the Pancreas: A Comprehensive Review.

Authors:  Gregory W Charville; Chia-Sui Kao
Journal:  Arch Pathol Lab Med       Date:  2018-09       Impact factor: 5.534

5.  Unilocular macrocystic serous cystadenoma of the pancreas--atypical features: a case report.

Authors:  Inês Leite; Marta Palmeiro; Alessandra Farchione; Celso Matos; Maria Antonieta Bali; Pieter Demetter; Myriam Delhaye
Journal:  Clin Imaging       Date:  2013-12-21       Impact factor: 1.605

6.  Benign macrocystic serous cystadenoma of the pancreas.

Authors:  Selma Erdogan Duzcu; Nur Tunc
Journal:  Indian J Pathol Microbiol       Date:  2021-06       Impact factor: 0.740

7.  Serous cystic neoplasms of the pancreas: an immunohistochemical analysis revealing alpha-inhibin, neuron-specific enolase, and MUC6 as new markers.

Authors:  Markus Kosmahl; Janning Wagner; Katharina Peters; Bence Sipos; Günter Klöppel
Journal:  Am J Surg Pathol       Date:  2004-03       Impact factor: 6.394

8.  Use of cyst fluid CEA, CA19-9, and amylase for evaluation of pancreatic lesions.

Authors:  Christine L H Snozek; Ranjan C Mascarenhas; Dennis J O'Kane
Journal:  Clin Biochem       Date:  2009-07-02       Impact factor: 3.281

9.  The CARE guidelines: consensus-based clinical case reporting guideline development.

Authors:  Joel J Gagnier; Gunver Kienle; Douglas G Altman; David Moher; Harold Sox; David Riley
Journal:  Headache       Date:  2013 Nov-Dec       Impact factor: 5.887

10.  Pancreatic cyst fluid analysis for differential diagnosis between benign and malignant lesions.

Authors:  Renata Talar-Wojnarowska; Marek Pazurek; Lukasz Durko; Malgorzata Degowska; Grazyna Rydzewska; Jacek Smigielski; Adam Janiak; Marek Olakowski; Paweł Lampe; Piotr Grzelak; Ludomir Stefanczyk; Ewa Malecka-Panas
Journal:  Oncol Lett       Date:  2012-12-12       Impact factor: 2.967

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