Literature DB >> 36259127

99mTc-methylene diphosphonate SPECT/CT imaging of gout spondylitis: a case report.

Yan Wang1, Yan Zha2, Rongfeng She3, Gaofeng Sun4, Shuang Li5, Lin Liu6, Neil Roberts7, Yaying Li1.   

Abstract

Single-photon emission computed tomography (SPECT)/computed tomography (CT) imaging of the gouty spine is rare. We describe a 66-year-old man who presented with pain and numbness in the right lower leg; he reported a 2-month history of intermittent low back pain. Imaging revealed neoplastic lesions of the spine, which were initially regarded as tumors. Thus, the patient underwent surgical removal of the lumbar lesion. However, the postoperative pathological diagnosis was gout spondylitis. In this report, we show multimodal images of advanced gout spondylitis. The metabolic information provided by SPECT/CT, combined with the microscopic changes in bone structure revealed by dual-source thin-layer CT and the anatomical localization information provided by magnetic resonance imaging, can help clinicians to more fully understand the pathophysiological mechanisms and imaging manifestations of gout from multiple perspectives, thereby reducing the rate of misdiagnosis.

Entities:  

Keywords:  Gout spondylitis; case report; computed tomography; magnetic resonance imaging; methylene disphosphonate; single-photon emission computed tomography

Mesh:

Substances:

Year:  2022        PMID: 36259127      PMCID: PMC9583207          DOI: 10.1177/03000605221129557

Source DB:  PubMed          Journal:  J Int Med Res        ISSN: 0300-0605            Impact factor:   1.573


  18 in total

1.  Chronic tophaceous gout: scintigraphic findings on bone scan.

Authors:  E Goshen; A Schwartz; S T Zwas
Journal:  Clin Nucl Med       Date:  2000-02       Impact factor: 7.794

Review 2.  An evidence-based review of quantitative SPECT imaging and potential clinical applications.

Authors:  Dale L Bailey; Kathy P Willowson
Journal:  J Nucl Med       Date:  2013-01       Impact factor: 10.057

Review 3.  Radionuclide joint imaging.

Authors:  P B Hoffer; H K Genant
Journal:  Semin Nucl Med       Date:  1976-01       Impact factor: 4.446

4.  The unclosing premature mortality gap in gout: a general population-based study.

Authors:  Mark C Fisher; Sharan K Rai; Na Lu; Yuqing Zhang; Hyon K Choi
Journal:  Ann Rheum Dis       Date:  2017-01-25       Impact factor: 19.103

Review 5.  Gout.

Authors:  Nicola Dalbeth; Anna L Gosling; Angelo Gaffo; Abhishek Abhishek
Journal:  Lancet       Date:  2021-03-30       Impact factor: 79.321

Review 6.  Gout in the Spine: Imaging, Diagnosis, and Outcomes.

Authors:  Michael Toprover; Svetlana Krasnokutsky; Michael H Pillinger
Journal:  Curr Rheumatol Rep       Date:  2015-12       Impact factor: 4.592

7.  Comorbidity clusters in people with gout: an observational cohort study with linked medical record review.

Authors:  Megan Bevis; Milisa Blagojevic-Bucknall; Christian Mallen; Samantha Hider; Edward Roddy
Journal:  Rheumatology (Oxford)       Date:  2018-08-01       Impact factor: 7.580

8.  Spinal and sacroiliac gouty arthritis: report of a case and review of the literature.

Authors:  Fabiano Nassar Cardoso; Patrick Omoumi; Gregoire Wieers; Baudouin Maldague; Jacques Malghem; Frédéric E Lecouvet; Bruno C Vande Berg
Journal:  Acta Radiol Short Rep       Date:  2014-09-17

9.  Spinal gout: A review with case illustration.

Authors:  Hossein Elgafy; Xiaochen Liu; Joseph Herron
Journal:  World J Orthop       Date:  2016-11-18

10.  Hyperuricemia and deterioration of renal function in autosomal dominant polycystic kidney disease.

Authors:  Miyeun Han; Hayne Cho Park; Hyunsuk Kim; Hyung Ah Jo; Hyuk Huh; Joon Young Jang; Ah-Young Kang; Seung Hyup Kim; Hae Il Cheong; Duk-Hee Kang; Jaeseok Yang; Kook-Hwan Oh; Young-Hwan Hwang; Curie Ahn
Journal:  BMC Nephrol       Date:  2014-04-16       Impact factor: 2.388

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