Literature DB >> 36257930

IKKβ binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses.

Yaw Asare1, Margarita Shnipova2, Luka Živković2, Christina Schlegl2, Federica Tosato2, Arailym Aronova2, Markus Brandhofer2, Laura Strohm3, Nathalie Beaufort2, Rainer Malik2, Christian Weber3,4, Jürgen Bernhagen2,3, Martin Dichgans5,6.   

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Year:  2022        PMID： 36257930      PMCID： PMC9579124          DOI： 10.1038/s41392-022-01189-3

Source DB:  PubMed          Journal:  Signal Transduct Target Ther        ISSN： 2059-3635


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  6 in total

1.  Antiinflammatory Therapy with Canakinumab for Atherosclerotic Disease.

Authors:  Paul M Ridker; Brendan M Everett; Tom Thuren; Jean G MacFadyen; William H Chang; Christie Ballantyne; Francisco Fonseca; Jose Nicolau; Wolfgang Koenig; Stefan D Anker; John J P Kastelein; Jan H Cornel; Prem Pais; Daniel Pella; Jacques Genest; Renata Cifkova; Alberto Lorenzatti; Tamas Forster; Zhanna Kobalava; Luminita Vida-Simiti; Marcus Flather; Hiroaki Shimokawa; Hisao Ogawa; Mikael Dellborg; Paulo R F Rossi; Roland P T Troquay; Peter Libby; Robert J Glynn
Journal:  N Engl J Med       Date:  2017-08-27       Impact factor: 91.245

Review 2.  The NLRP3 inflammasome: molecular activation and regulation to therapeutics.

Authors:  Karen V Swanson; Meng Deng; Jenny P-Y Ting
Journal:  Nat Rev Immunol       Date:  2019-08       Impact factor: 53.106

Review 3.  Toll-like Receptors and the Control of Immunity.

Authors:  Katherine A Fitzgerald; Jonathan C Kagan
Journal:  Cell       Date:  2020-03-11       Impact factor: 66.850

4.  IKKβ is required for the formation of the NLRP3 inflammasome.

Authors:  Sambit K Nanda; Alan R Prescott; Clara Figueras-Vadillo; Philip Cohen
Journal:  EMBO Rep       Date:  2021-08-17       Impact factor: 8.807

5.  IRAK-1 bypasses priming and directly links TLRs to rapid NLRP3 inflammasome activation.

Authors:  Keng-Mean Lin; Wei Hu; Ty Dale Troutman; Michelle Jennings; Travis Brewer; Xiaoxia Li; Sambit Nanda; Philip Cohen; James A Thomas; Chandrashekhar Pasare
Journal:  Proc Natl Acad Sci U S A       Date:  2013-12-30       Impact factor: 11.205

6.  PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation.

Authors:  Jueqi Chen; Zhijian J Chen
Journal:  Nature       Date:  2018-11-28       Impact factor: 69.504
  6 in total

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