| Literature DB >> 36255615 |
Abstract
One of the main characteristics of cancer is the rapid proliferation of transformed cells. Cancer therapies aim to kill such cells. Cancer clones surviving therapy can be resistant to the treatment, but they can also lose the ability to proliferate. The ability of single cells to proliferate can be monitored in vitro and can provide insights into the sensitivity of tumor cells to chemotherapeutics. The following chapter describes how clonogenic hematopoietic cell growth can be determined with the colony formation assay.Entities:
Keywords: Colony formation; HDAC; Hematopoietic cells; Leukemia; Methyl cellulose; Proliferation; Survival
Mesh：
Year: 2023 PMID： 36255615 DOI： 10.1007/978-1-0716-2788-4_2
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745