| Literature DB >> 36250482 |
Yaqian Li1, Guangcai Yu1,2, Longke Shi1,3, Liwen Zhao1,3, Zixin Wen1,4, Baotian Kan1,4, Wenjun Wang1,4, Xiangdong Jian1,2,3.
Abstract
Methyl bromide is a pre-plant soil fumigant that is widely used to control nematodes, insects, and fungi in farmlands. Methyl bromide enters the human body through dermal absorption or inhalation and can damage the respiratory, nervous, circulatory, urinary, and other systems. A 62-year-old man who had inhaled a large amount of methyl bromide was admitted to our department. He presented with respiratory failure and pink foamy sputum. He was started on dexamethasone, alanyl glutamine, sulbactam, furosemide, vitamin B1, mouse nerve growth factor, and other treatments, and mechanical ventilation and continuous venovenous hemodiafiltration (CVVHF) were performed daily. He subsequently developed coagulopathy because of the CVVHF, for which protamine, recombinant human brain natriuretic peptide, and albumin were administered intravenously. Notably, the patient developed sustained anuria and eventually died owing to multiple organ failure; specifically, failure of the brain, heart, lungs, and kidneys. This report presents the diagnosis, clinical course, management, and prognosis of a patient who was treated at our hospital for severe methyl bromide poisoning.Entities:
Keywords: Acute renal failure; anuria; continuous venovenous hemodiafiltration; diagnosis; methyl bromide; multiple organ failure; poisoning; prognosis; respiratory inhalation
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Year: 2022 PMID: 36250482 PMCID: PMC9578171 DOI: 10.1177/03000605221122619
Source DB: PubMed Journal: J Int Med Res ISSN: 0300-0605 Impact factor: 1.573