Literature DB >> 36250482

Severe methyl bromide poisoning causing early acute renal failure and anuria: a case report.

Yaqian Li1, Guangcai Yu1,2, Longke Shi1,3, Liwen Zhao1,3, Zixin Wen1,4, Baotian Kan1,4, Wenjun Wang1,4, Xiangdong Jian1,2,3.   

Abstract

Methyl bromide is a pre-plant soil fumigant that is widely used to control nematodes, insects, and fungi in farmlands. Methyl bromide enters the human body through dermal absorption or inhalation and can damage the respiratory, nervous, circulatory, urinary, and other systems. A 62-year-old man who had inhaled a large amount of methyl bromide was admitted to our department. He presented with respiratory failure and pink foamy sputum. He was started on dexamethasone, alanyl glutamine, sulbactam, furosemide, vitamin B1, mouse nerve growth factor, and other treatments, and mechanical ventilation and continuous venovenous hemodiafiltration (CVVHF) were performed daily. He subsequently developed coagulopathy because of the CVVHF, for which protamine, recombinant human brain natriuretic peptide, and albumin were administered intravenously. Notably, the patient developed sustained anuria and eventually died owing to multiple organ failure; specifically, failure of the brain, heart, lungs, and kidneys. This report presents the diagnosis, clinical course, management, and prognosis of a patient who was treated at our hospital for severe methyl bromide poisoning.

Entities:  

Keywords:  Acute renal failure; anuria; continuous venovenous hemodiafiltration; diagnosis; methyl bromide; multiple organ failure; poisoning; prognosis; respiratory inhalation

Mesh:

Substances:

Year:  2022        PMID: 36250482      PMCID: PMC9578171          DOI: 10.1177/03000605221122619

Source DB:  PubMed          Journal:  J Int Med Res        ISSN: 0300-0605            Impact factor:   1.573


  16 in total

1.  Methylbromide intoxication: a clinical case study.

Authors:  Wim Breeman
Journal:  Adv Emerg Nurs J       Date:  2009 Apr-Jun

2.  The methylation of wool with methyl sulphate and methyl halides.

Authors:  S Blackburn; E G Carter; H Phillips
Journal:  Biochem J       Date:  1941-06       Impact factor: 3.857

Review 3.  The neurological effects of methyl bromide intoxication.

Authors:  Aaron de Souza; Kedareshwar P S Narvencar; K V Sindhoora
Journal:  J Neurol Sci       Date:  2013-09-20       Impact factor: 3.181

4.  Three cases of acute methyl bromide poisoning in a seedling farm family.

Authors:  Y Yamano; J Kagawa; S Ishizu; O Harayama
Journal:  Ind Health       Date:  2001-10       Impact factor: 2.179

Review 5.  The unusual presentation of a burn from methyl bromide exposure: A case report and review of the literature.

Authors:  Gloria R Sue; Yvonne L Karanas; Drew J Davis; Barry Press
Journal:  Burns       Date:  2017-01-06       Impact factor: 2.744

6.  Methyl bromide exposure and cancer risk in the Agricultural Health Study.

Authors:  Kathryn Hughes Barry; Stella Koutros; Jay H Lubin; Joseph B Coble; Francesco Barone-Adesi; Laura E Beane Freeman; Dale P Sandler; Jane A Hoppin; Xiaomei Ma; Tongzhang Zheng; Michael C R Alavanja
Journal:  Cancer Causes Control       Date:  2012-04-24       Impact factor: 2.506

7.  Cases from NACCT acute and intensive care symposium: altered mental status, seizures, and rash in a fumigation company employee.

Authors:  Paul E Stromberg; Kirk L Cumpston
Journal:  Clin Toxicol (Phila)       Date:  2013-03       Impact factor: 4.467

8.  A Case Report of Toxic Brain Syndrome Caused by Methyl Bromide.

Authors:  Sibel Büyükçoban; Mualla Aylin Arıcı; Uğur Koca; Şule Kalkan
Journal:  Turk J Anaesthesiol Reanim       Date:  2015-02-05

9.  Methyl bromide intoxication in four field-workers during removal of soil fumigation sheets.

Authors:  J Herzstein; M R Cullen
Journal:  Am J Ind Med       Date:  1990       Impact factor: 2.214

10.  Disposition of [14C]methyl bromide in rats after inhalation.

Authors:  J A Bond; J S Dutcher; M A Medinsky; R F Henderson; L S Birnbaum
Journal:  Toxicol Appl Pharmacol       Date:  1985-04       Impact factor: 4.219

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