Literature DB >> 3624820

[Cutaneous angiosarcoma of the breast following surgery and irradiation of breast adenocarcinoma].

G Body, E Sauvanet, G Calais, A Fignon, F Fetissof, J Lansac.   

Abstract

We are reporting a localised skin angiosarcoma of the breast. As far as we can tell this is only the fourth time this condition has been published. The tumour appeared 6 years after a conservative lumpectomy with removal of lymphatics and follow-up radiotherapy had been carried out for an adenocarcinoma of the breast. This tumour was characterised by the presence of several round blue-coloured nodules in the skin with some inflammation surrounding them. The glandular tissue underneath was normal, as was the opposite breast, and there was no spread. The patient was pyrexial and a syndrome of inflammation persisted until the tumour had been removed by a simple mastectomy. We have discussed the clinical and histological aspects of this case and compared them with those found in the literature. Differential diagnosis with in particular Stewart-Treves syndrome has been emphasized. The treatment consists in wide excision and sometimes followed by radiotherapy or chemotherapy. The prognosis is very poor, survival never having been more than 22 months. Finally the role of irradiation in the causation of this tumour has been discussed. (Our patient is alive after 2 years without any sign of a recurrence).

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Mesh:

Year:  1987        PMID: 3624820

Source DB:  PubMed          Journal:  J Gynecol Obstet Biol Reprod (Paris)        ISSN: 0150-9918


  4 in total

1.  Angiosarcoma of the skin overlying an irradiated breast.

Authors:  R A Badwe; A M Hanby; I S Fentiman; M A Chaudary
Journal:  Breast Cancer Res Treat       Date:  1991-09       Impact factor: 4.872

2.  Radiation-associated angiosarcoma after breast cancer: high recurrence rate and poor survival despite surgical treatment with R0 resection.

Authors:  Jojanneke M Seinen; Emelie Styring; Vincent Verstappen; Fredrik Vult von Steyern; Anders Rydholm; Albert J H Suurmeijer; Harald J Hoekstra
Journal:  Ann Surg Oncol       Date:  2012-03-31       Impact factor: 5.344

3.  Key roles for MYC, KIT and RET signaling in secondary angiosarcomas.

Authors:  E Styring; J Seinen; M Dominguez-Valentin; H A Domanski; M Jönsson; F V von Steyern; H J Hoekstra; A J H Suurmeijer; M Nilbert
Journal:  Br J Cancer       Date:  2014-07-01       Impact factor: 7.640

4.  Late recurrent cutaneous breast angiosarcoma in an elderly woman: A case report.

Authors:  Fausto Fama'; Luana Licata; Alessandra Villari; Jessica Palella; Giuseppe Speciale; Maria Gioffre'-Florio
Journal:  Oncol Lett       Date:  2016-03-29       Impact factor: 2.967

  4 in total

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