Chunlei Li1, Wenbin Cui1, Panpan Song1, Wang Liu2, Xiaodong Wang3, Qiang Yang1. 1. Department of Anesthesiology, Cangzhou Central Hospital Cangzhou 061000, Hebei, China. 2. Department of Anesthesiology, Children's Ward of Cangzhou Central Hospital Cangzhou 061000, Hebei, China. 3. Department of Anesthesiology, Cangzhou Integrated Traditional Chinese and Western Medicine Hospital Cangzhou 061000, Hebei, China.
Abstract
OBJECTIVE: To evaluate the preventive effect of preoperative administration of ondansetron on postoperative nausea and vomiting (PONV) in patients receiving breast cancer surgery. METHODS: Data from 225 patients who received modified radical mastectomy from January 2019 to December 2020 were retrospectively reviewed. The patients were divided into an ondansetron group and a control group according to whether they received preoperative ondansetron or not. The incidence of PONV, visual analog scale (VAS) score, the rescue analgesics use and rescue antiemetic use, as well as the patient satisfaction degree about their PONV were compared between the two groups. RESULTS: The ondansetron group showed lower total incidence of PONV, lower VAS score at 6 h post-operation as well as less rescue antiemetic use than the control group (P<0.05). Patients in the ondansetron group were more satisfied with their PONV condition than those in the control group (P<0.05). CONCLUSION: Preoperative administration of ondansetron can prevent PONV and relieve pain 2-24 hours after breast cancer surgery. AJTR
OBJECTIVE: To evaluate the preventive effect of preoperative administration of ondansetron on postoperative nausea and vomiting (PONV) in patients receiving breast cancer surgery. METHODS: Data from 225 patients who received modified radical mastectomy from January 2019 to December 2020 were retrospectively reviewed. The patients were divided into an ondansetron group and a control group according to whether they received preoperative ondansetron or not. The incidence of PONV, visual analog scale (VAS) score, the rescue analgesics use and rescue antiemetic use, as well as the patient satisfaction degree about their PONV were compared between the two groups. RESULTS: The ondansetron group showed lower total incidence of PONV, lower VAS score at 6 h post-operation as well as less rescue antiemetic use than the control group (P<0.05). Patients in the ondansetron group were more satisfied with their PONV condition than those in the control group (P<0.05). CONCLUSION: Preoperative administration of ondansetron can prevent PONV and relieve pain 2-24 hours after breast cancer surgery. AJTR
Authors: Guilherme Oliveira Campos; Marcelo de Jesus Martins; Gabriel Nascimento Jesus; Paulo Roberto Rios de Oliveira; Caio Nogueira Lessa; João Carlos Macêdo Fernandes de Oliveira Junior; Lucas Jorge Santana de Castro Alves; Rodrigo Leal Alves; Norma Sueli Pinheiro Módolo Journal: BMC Anesthesiol Date: 2019-08-17 Impact factor: 2.217
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