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Literature DB >> 3624501

Accumulation of ceroid in smooth muscle indicates severe malabsorption and vitamin E deficiency.

Abstract

Four patients had accumulation of ceroid in smooth muscle (lipofuscinosis), which indicated severe or uncontrolled malabsorption, with confirmed vitamin E deficiency in three cases. The distribution of the pigment was systematic, and there seemed to be an association between malabsorption syndrome and vitamin E deficiency. Vitamin E supplementation seems to be indicated in such patients, and it is suggested that studies of smooth muscle function should be made in cases of heavy accumulation of ceroid.

Entities: Chemical Disease Species

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Year: 1987 PMID： 3624501 PMCID： PMC1141101 DOI： 10.1136/jcp.40.7.798

Source DB: PubMed Journal: J Clin Pathol ISSN： 0021-9746 Impact factor: 3.411

18 in total

Accumulation of ceroid in smooth muscle indicates severe malabsorption and vitamin E deficiency.

1. The Noonan syndrome with intestinal lymphangiectasia.

2. The absorption of alpha-tocopherol in control subjects and in patients with intestinal malabsorption.

3. Progressive neuropathologic lesions in vitamin E-deficient rhesus monkeys.

4. Brown bowel syndrome in Crohn's disease.

5. Perspective on vitamin E as therapy.

6. Brown pigmentation (lipofuscinosis) of canine intestinal muscularis.

Review 7. The brown bowel syndrome: a possible smooth muscle mitochondrial myopathy?

8. The relative importance of the factors involved in the absorption of vitamin E in children.

9. Lipofuscinosis of the gastrointestinal tract in man.

10. Ceroid enteropathy and vitamin E deficiency.

1. [A rare cause of small bowel ileus].

2. Massive lower gastrointestinal bleeding in association with the brown bowel syndrome.

3. Vascular smooth muscle lipofuscinosis occurring predominantly in veins of a cynomolgus monkey (Macaca fascicularis).