| Literature DB >> 3624241 |
M Fukuda, M Lauffenburger, H Sasaki, M E Rogers, A Dell.
Abstract
The O-linked oligosaccharides attached to human erythrocyte glycophorins were extensively characterized. In addition to the previously described disialylated tetrasaccharide, NeuNAc alpha 2----3Gal beta 1----3 (Neu-NAc alpha 2----6)GalNAcOH and monosialylated trisaccharide, NeuNAc alpha 2----3Gal beta 1----3GalNAcOH, novel trisialylated oligosaccharides were isolated. Methylation analysis, fast atom bombardment-mass spectrometry, and enzymatic degradation were used to elucidate the following novel structures: formula; see text: These results suggest that O-linked oligosaccharides with a disialosyl group, NeuNAc alpha 2----8NeuNAc alpha 2----, may be present in various tissues.Entities:
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Year: 1987 PMID: 3624241
Source DB: PubMed Journal: J Biol Chem ISSN: 0021-9258 Impact factor: 5.157