Literature DB >> 36241849

Scaffolds: a biomaterial engineering in targeted drug delivery for osteoporosis.

Safoora Poorirani1, Sayed Latif Taheri1, Sayed Abolfazl Mostafavi2.   

Abstract

Osteoporosis is an increasingly common condition that causes low bone density, porous bone, and increased fracture risk. Treatments for osteoporosis are divided into two categories: (a) antiresorptive and (b) anabolic. To decrease side effects of drug and dosage level variations caused by several consecutive administrations, various drug delivery systems have been proposed. Among them, scaffolds are one of the drug delivery systems that led to drug impart with high loading and suitable efficiency to specific sites which retain active agents at acceptable therapeutic levels. The purpose of this review was to explain the role of scaffolds in targeted drug delivery to bone tissue for the treatment of osteoporosis.
© 2022. International Osteoporosis Foundation and Bone Health and Osteoporosis Foundation.

Entities:  

Keywords:  Biomaterial engineering; Drug delivery; Osteoporosis; Scaffold; Targeted

Year:  2022        PMID: 36241849     DOI: 10.1007/s00198-022-06543-3

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   5.071


  40 in total

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Authors:  Dima L Diab; Nelson B Watts
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Review 9.  Teriparatide: a review of its use in osteoporosis.

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Review 10.  Gallium containing bioactive materials: A review of anticancer, antibacterial, and osteogenic properties.

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