Literature DB >> 36237752

Metastatic Testicular Seminoma in a Patient With Down Syndrome Presenting As Extensive Deep Venous Thrombosis.

Meredith Hengy1, Amita Hinge1, James P Purtell2, Kathren Shango2, Joshua Collins2.   

Abstract

Testicular cancer, particularly seminoma, is associated with Down syndrome. In cognitively impaired patients, the typical presenting signs of testicular cancer may be missed, and atypical presenting features may be the only clue to the diagnosis. In this report, we present the case of a 38-year-old male who presented with extensive deep vein thrombosis in the setting of seminoma.
Copyright © 2022, Hengy et al.

Entities:  

Keywords:  cancer screening; deep vein thrombosis; down syndrome; seminoma; testicular cancer

Year:  2022        PMID： 36237752      PMCID： PMC9552953          DOI： 10.7759/cureus.29037

Source DB:  PubMed          Journal:  Cureus        ISSN： 2168-8184


  16 in total

Review 1.  Testicular seminoma: oncologic rationale and role of surgery in treatment.

Authors:  Nitin K Yerram; Hans C Arora; Abhinav Khanna; Kyle Ericson; Andrew Y Sun; Paurush Babbar; Naveen Nandanan; Andrew J Stephenson
Journal:  Clin Adv Hematol Oncol       Date:  2017-09

Review 2.  Cancer screening in adults with down syndrome, a proposal.

Authors:  Marie-Odile Rethoré; Jacques Rouëssé; Daniel Satgé
Journal:  Eur J Med Genet       Date:  2019-10-09       Impact factor: 2.708

Review 3.  [Testicular germ cell tumors: Histopathological and molecular features].

Authors:  Morgan Tourne; Camelia Radulescu; Yves Allory
Journal:  Bull Cancer       Date:  2019-03-21       Impact factor: 1.276

Review 4.  Testicular cancer: seminoma.

Authors:  Peter Chung; Padraig Warde
Journal:  BMJ Clin Evid       Date:  2011-01-25

Review 5.  Testicular cancer: a prototypic tumor of young adults.

Authors:  Brandon Hayes-Lattin; Craig R Nichols
Journal:  Semin Oncol       Date:  2009-10       Impact factor: 4.929

Review 6.  Somatic KIT mutations occur predominantly in seminoma germ cell tumors and are not predictive of bilateral disease: report of 220 tumors and review of literature.

Authors:  Jerome Coffey; Rachel Linger; Julia Pugh; Darshna Dudakia; Michael Sokal; Douglas F Easton; D Timothy Bishop; Michael Stratton; Robert Huddart; Elizabeth A Rapley
Journal:  Genes Chromosomes Cancer       Date:  2008-01       Impact factor: 5.006

7.  Testicular Germ-Cell Tumours: A Descriptive Analysis of Clinical Characteristics at First Presentation.

Authors:  Klaus-Peter Dieckmann; Hanna Richter-Simonsen; Magdalena Kulejewski; Raphael Ikogho; Henrik Zecha; Petra Anheuser; Uwe Pichlmeier; Hendrik Isbarn
Journal:  Urol Int       Date:  2018-04-12       Impact factor: 2.089

8.  Exploration of the treatment challenges in men with intellectual difficulties and testicular cancer as seen in Down syndrome: single centre experience.

Authors:  Shaista Hafeez; Mausam Singhera; Robert Huddart
Journal:  BMC Med       Date:  2015-06-26       Impact factor: 8.775

9.  Testicular cancer in Down syndrome with spinal cord metastases.

Authors:  Turky Almouhissen; Hattan Badr; Bassam AlMatrafi; Noor Alessa; Anmar Nassir
Journal:  Urol Ann       Date:  2016 Oct-Dec

Review 10.  Cannabinoid Receptors Signaling in the Development, Epigenetics, and Tumours of Male Germ Cells.

Authors:  Marco Barchi; Elisa Innocenzi; Teresa Giannattasio; Susanna Dolci; Pellegrino Rossi; Paola Grimaldi
Journal:  Int J Mol Sci       Date:  2019-12-18       Impact factor: 5.923
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