Laure Jacquemin1,2, Sara Demoen3,4,5, Sarah Michiels6,1, Annick Gilles1,2,7, Hanne Vermeersch1, Iris Joossen1, Olivier M Vanderveken1,2, Marc J W Lammers1,2, Annick Timmermans6, Vincent Van Rompaey1,2, David Baguley8,9,10. 1. Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, 2650, Edegem, Belgium. 2. Department of Translational Neurosciences, Faculty of Medicine and Health Sciences, University Antwerp, 2610, Antwerp, Belgium. 3. Rehabilitation Research Center, REVAL, Faculty of Rehabilitation Sciences, Hasselt University, Hasselt University Campus Diepenbeek, Agoralaan, 3500, Hasselt, Belgium. sara.demoen@uhasselt.be. 4. Department of Otorhinolaryngology and Head and Neck Surgery, Antwerp University Hospital, 2650, Edegem, Belgium. sara.demoen@uhasselt.be. 5. Department of Translational Neurosciences, Faculty of Medicine and Health Sciences, University Antwerp, 2610, Antwerp, Belgium. sara.demoen@uhasselt.be. 6. Rehabilitation Research Center, REVAL, Faculty of Rehabilitation Sciences, Hasselt University, Hasselt University Campus Diepenbeek, Agoralaan, 3500, Hasselt, Belgium. 7. Department of Education, Health and Social Work, University College Ghent, 9000, Ghent, Belgium. 8. Hearing Sciences, Division of Clinical Neurosciences, School of Medicine, University of Nottingham, Nottingham, 0115, UK. 9. National Institute for Health Research (NIHR) Nottingham Biomedical Research Centre, Nottingham, 0115, UK. 10. Nottingham Audiology Services, Nottingham University Hospitals NHS Trust, Nottingham, 0115, UK.
Abstract
BACKGROUND: Hyperacusis is a reduced tolerance to sounds that often co-occurs with tinnitus. Both symptoms have convergent as well as divergent characteristics. Somatic modulation, changes in pitch or loudness during certain movements, is common in patients with a primary complaint of tinnitus. However, thus far, this is not documented in patients with hyperacusis. OBJECTIVES: This study aimed to examine the influence of somatic manoeuvres on the perception of external sounds in patients with a primary complaint of hyperacusis. METHODOLOGY: In this prospective cross-sectional pilot study, 18 patients with a primary complaint of hyperacusis were recruited at the Tinnitus Treatment and Research Center Antwerp (TINTRA). While patients listened to a 1 kHz broadband noise of 30 dB sensation level, six neck manoeuvres (flexion, extension, lateroflexion left/right, traction and compression), three jaw manoeuvres (protrusion, laterotrusion left/right) and one placebo manoeuvre (hand on head) were performed. The primary outcome measure was the change in the perception of the presented sound in terms of loudness and intrusiveness between baseline and each modulation measured by a visual analogue scale (VAS). RESULTS: No overall significant changes were found; however, individual results indicated that five patients presented a clinically relevant change of more than three points out of ten on VAS in terms of hyperacusis after at least one of the executed somatic manoeuvres. CONCLUSIONS: This pilot study did not demonstrate an overall significant change in hyperacusis after somatic manoeuvres but does not rule out the possibility of somatic modulation in some hyperacusis patients. TRIAL REGISTRATION: The protocol of this prospective cross-sectional pilot study was registered on clinicaltrials.gov with registration number NCT04693819.
BACKGROUND: Hyperacusis is a reduced tolerance to sounds that often co-occurs with tinnitus. Both symptoms have convergent as well as divergent characteristics. Somatic modulation, changes in pitch or loudness during certain movements, is common in patients with a primary complaint of tinnitus. However, thus far, this is not documented in patients with hyperacusis. OBJECTIVES: This study aimed to examine the influence of somatic manoeuvres on the perception of external sounds in patients with a primary complaint of hyperacusis. METHODOLOGY: In this prospective cross-sectional pilot study, 18 patients with a primary complaint of hyperacusis were recruited at the Tinnitus Treatment and Research Center Antwerp (TINTRA). While patients listened to a 1 kHz broadband noise of 30 dB sensation level, six neck manoeuvres (flexion, extension, lateroflexion left/right, traction and compression), three jaw manoeuvres (protrusion, laterotrusion left/right) and one placebo manoeuvre (hand on head) were performed. The primary outcome measure was the change in the perception of the presented sound in terms of loudness and intrusiveness between baseline and each modulation measured by a visual analogue scale (VAS). RESULTS: No overall significant changes were found; however, individual results indicated that five patients presented a clinically relevant change of more than three points out of ten on VAS in terms of hyperacusis after at least one of the executed somatic manoeuvres. CONCLUSIONS: This pilot study did not demonstrate an overall significant change in hyperacusis after somatic manoeuvres but does not rule out the possibility of somatic modulation in some hyperacusis patients. TRIAL REGISTRATION: The protocol of this prospective cross-sectional pilot study was registered on clinicaltrials.gov with registration number NCT04693819.
Authors: Richard S Tyler; Martin Pienkowski; Eveling Rojas Roncancio; Hyung Jin Jun; Tom Brozoski; Nicolas Dauman; Nicolas Dauman; Gerhard Andersson; Andrew J Keiner; Anthony T Cacace; Nora Martin; Brian C J Moore Journal: Am J Audiol Date: 2014-12 Impact factor: 1.493